Results 31 to 40 of about 41,997 (258)

Strengthening global health security through antimicrobial resistance control: Insights from Saudi Arabia

Journal of Infection and Public Health
Antimicrobial resistance (AMR) poses a significant threat to global health security, and Saudi Arabia plays a key role in addressing this challenge. This review highlights Saudi Arabia’s National Action Plan, which focuses on improving data collection ...
Haytham A. Sheerah, Abdullah R. Algwizani, Riyad Q. Alghamdi, Emad L. Almohammadi, Ada M. Al-Qunaibe, Hebah M. Dada, Homoud S. Algarni, Safaa M. Tunkar, Asmaa M. Altamimi, Yasir S. Almuzaini, Duncan Selbie   +10 more
doaj   +1 more source

An authorization model for query execution in the cloud [PDF]

The VLDB Journal, 2021
Sabrina De Capitani di Vimercati, Sara Foresti, Sushil Jajodia, Giovanni Livraga, Stefano Paraboschi, Pierangela Samarati   +5 more
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Political reforms in Jordan following the events of the Arab Spring

RUDN Journal of Public Administration, 2019
Following the events of the Arab Spring and the popular protests that broke out in some countries in the Arab world in 2011, including Jordan, extended political reforms were carried out in Jordan, including major constitutional amendments and ...
Mazen Hussien Faleh Hawamdeh, Ahmad Saher Ahmad Al-Qteishat   +1 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

سلطة التشريع بالأوامر في التشريع التشادي في ظل دستور ديسمبر لعام 2023 / Legislative Power by Decree in Chadian Legislation at the Constitution of the December 2023 [PDF]

مجلة البحوث الفقهیة والقانونیة
لقد ذهب المشرّع التشادي إلى اعتماد خاصية منح رئيس الجمهورية سلطة التشريع بالأوامر بموجب المادة: (137) من الدستور، وذلك خلال آجال محددة وردت في هذه المادة.
محمّد البشير بن أحمد موسى يغقوب
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source