Results 31 to 40 of about 1,541,162 (315)

Ekaterinburg (Sverdlovsk) During NEP Years: Organization of City Government System

open access: yesНаучный диалог, 2023
The article discusses the activities of various levels of government structures (city council, gubernatorial, district and regional executive and party bodies) in managing EkaterinburgSverdlovsk during the NEP years.
S. V. Vorobyov
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

PROBLEMS OF DEMOCRACY: A NEW VIEW. BOOK REVIEW: DEMOCRACY: EXPERIENCE OF CRITICAL ANALYSIS. BY A.D. KERIMOV. MOSCOW. NORMA, 2019

open access: yesRUDN Journal of Law, 2019
The peer-reviewed book is the first and only domestic publication in which the critique of democracy as a sociocultural and political-legal phenomenon is amply and concentratedly presented. The author confidently proves that democracy is not the power of
Anisim I. Ekimov
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Zivotofsky II and National Security Decisionmaking at the Lowest Ebb [PDF]

open access: yes, 2017
This Note examines assertions of exclusive presidential power in light of the Supreme Court’s 2015 decision in Zivotofsky ex rel. Zivotofsky v. Kerry.
Harrington, Chase
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Executive Power: Rethinking the Modalities of Control [PDF]

open access: yes, 2018
The Honorable Sundaresh Menon, Chief Justice of the Supreme Court of Singapore, delivered the 2018-2019 Bernstein Lecture in Comparative Law titled Executive Power: Rethinking the Modalities of Control.
Menon, Sundaresh
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Presidential Exit [PDF]

open access: yes, 2018
The biggest problem that we\u27re facing right now has to do with George Bush trying to bring more and more power into the executive branch and not go through Congress at all, and that\u27s what I intend to reverse when I\u27m president of the United ...
Ruhl, J.B., Salzman, James
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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