Results 31 to 40 of about 124,437 (265)

De « la voix de la France » à « l’État annonceur »

open access: yesCommunication, 2001
Today, communication is considered to be evident and necessary in French governmental institutions. However, the rendering systematic of the address to citizens by the executive power does not result solely from institutional changes, from the eternal ...
Caroline Ollivier-Yaniv
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Competition of State Powers During the COVID-19 Pandemic

open access: yesTeisė, 2022
The aim of this article is to analyse what kind of powers deriving from the rule of law can be extended to public authorities in response to the global COVID-19 pandemic, what is the balance of powers between the legislative and the executive whilst ...
Toma Birmontienė, Jolita Miliuvienė
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Administrative legal relations with the participation of the State Bureau of Investigation

open access: yesBulletin of Kharkiv National University of Internal Affairs
The essence, characteristics, and types of administrative legal relations involving the State Bureau of Investigations have been identified. Additionally, suggestions and recommendations for improving the legal foundations of these relations have been ...
А. Т. Komziuk, Ye. А. Lypii
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

REKONSTRUKSI SISTEM PERADILAN PIDANA INDONESIA DALAM PERSPEKTIF KEMANDIRIAN KEKUASAAN KEHAKIMAN

open access: yesMasalah-Masalah Hukum, 2012
Criminal justice system as a tool of law enforcement, didn't work optimally in Indonesia.  It often being used by executive power because its position and function didn't independent and subordinated by executive power.
Pujiyono Pujiyono
doaj   +1 more source

Institute of the President of Ukraine: dynamics of spheres of competence

open access: yesПолітичні дослідження, 2023
The article analyzes the process of formation and the role of the president’s institution in the structure of the executive power of Ukraine. The activity of the Institute of the President of Ukraine, as well as the specifics of its functioning in the ...
Oleh Kondratenko
doaj   +1 more source

Home - About - Disclaimer - Privacy