Results 51 to 60 of about 1,203,976 (314)
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Opportunities for Research in Mental Health Emergencies: Executive Summary and Methodology
Western Journal of Emergency Medicine, 2019 Introduction: Despite the ever-increasing numbers of mental health patients presenting to United States emergency departments, there are large gaps in knowledge about acute care of the behavioral health patient.
Michael P. Wilson +5 more
doaj +1 more source
Improving Global Financial Stability - Executive Summary [PDF]
, 2000 Executive summary of "Improving Global Financial Stability" report.
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SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
2010 Piscataqua Region Comprehensive : Executive Summary [PDF]
, 2010 In the fall of 2010, the Piscataqua Region Estuaries Partnership (PREP) completed an 18-month effort to understand current and future environmental issues affecting the Region’s estuaries, to establish realistic goals and objectives for the next 10 years,
Piscataqua Region Estuaries Partnership
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FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2024
Allergology InternationalThis is an abridged edition of English version of the Clinical Practice Guidelines for the Management of Atopic Dermatitis 2024. Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion.
Hidehisa Saeki +19 more
doaj +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Standards of Medical Care in Diabetes-2009 (American Diabetes Association): executive summary
Сахарный диабет, 2009 ?Стандарты оказания медицинской помощи больным сахарным диабетом?, рекомендуемые Американской диабетической ассоциацией (АДА), являются одним из основных документов, регламентирующих деятельность медицинских специалистов по диагностике и лечению данного ...
Olga Konstantinovna Vikulova
doaj +1 more source
ScratchMaths: evaluation report and executive summary [PDF]
, 2018 Since 2014, computing has been part of the primary curriculum. ‘Scratch’ is frequently used by schools, and the EEF funded this trial to test whether the platform could be used to improve pupils’ computational thinking skills, and whether this in turn ...
Boylan, Mark +4 more
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