Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher+6 more
wiley +1 more source
Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease [PDF]
Title: Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease. Purpose: This study examined the effects of a non-invasive ventilator on submaximal and maximal exercise performance in ...
Doggett, Anita
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We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin+2 more
wiley +1 more source
PENGARUH LATIHAN KONTINYU DAN INTERVAL TERHADAP KAPASITAS AEROBIK [PDF]
This research aims at studying: (1) The influence of continual exercise towards aerobic capacity, (2) The influence of interval exercise towards aerobic capacity, (3) The different effectiveness of continual and interval towards maximal aerobic capacity.
Margono, Suharjana, Suherman, Wawan S
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Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
The aquatic exercise is an effective non-pharmacological therapy for prevention and control of hypertension. The objective of the present study was to investigate the effect of aquatic exercise on mental health, functional autonomy, and oxidative ...
Luciano Acordi Da Silva+8 more
doaj +1 more source
Exercises for Children with Dyslalia-Software Infrastructure [PDF]
In order to help children with dyslalia we created a set of software exercises. This set has a unitary software block (data base, programming language, programming philosophy). In this paper we present this software infrastructure with its advantage and disadvantage. The exercises are part of a software system named LOGOMON.
arxiv
The influence of voluntary upper body exercise on the performance of stimulated paralysed human quadriceps [PDF]
In this study the influence of voluntary upper body exercise on the performance of stimulated paralysed human quadriceps was investigated in five subjects with spinal cord lesions in the thoracic spine.
Boom, H.B.K.+5 more
core +4 more sources
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra+7 more
wiley +1 more source
Common exercise prescription for management of weight and osteoarthritis : a systematic review : a thesis presented in partial fulfilment of the requirements for the degree of Master of Sport and Exercise at Massey University, Wellington, New Zealand [PDF]
Background: Obesity and osteoarthritis are two debilitating conditions that are increasing in prevalence. Obese populations are at an increased risk for developing osteoarthritis in later life.
Barrow, Dylan
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