Results 121 to 130 of about 5,869,609 (392)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

The impact of low energy availability risk on pre-competition physiological function in Chinese female combat athletes

Journal of the International Society of Sports Nutrition
Background Low energy availability (LEA) can negatively impact athletes’ physiological function and performance. This study aims to examine the prevalence of LEA in Chinese female combat athletes and monitor changes in physiological function and ...
Yiheng Liang, Yuxuan Li, Yan Chen, Kun Meng, Fanyang Zhou, Yiran Pei, Yong Liu, Junqiang Qiu   +7 more
doaj   +1 more source

PENGARUH LATIHAN KONTINYU DAN INTERVAL TERHADAP KAPASITAS AEROBIK [PDF]

, 2003
This research aims at studying: (1) The influence of continual exercise towards aerobic capacity, (2) The influence of interval exercise towards aerobic capacity, (3) The different effectiveness of continual and interval towards maximal aerobic capacity.
Margono, Suharjana, Suherman, Wawan S
core  

Exercise-Derived Microvesicles: A Review of the Literature [PDF]

, 2018
Initially suggested as simple cell debris, cell-derived microvesicles (MVs) have now gained acceptance as recognized players in cellular communication and physiology.
Mourot, Laurent, Rakobowchuk, Mark, Wilhelm, Eurico N.   +2 more
core   +2 more sources

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

Debunking the Myth of Exercise-Induced Immune Suppression: Redefining the Impact of Exercise on Immunological Health Across the Lifespan

Frontiers in Immunology, 2018
Epidemiological evidence indicates that regular physical activity and/or frequent structured exercise reduces the incidence of many chronic diseases in older age, including communicable diseases such as viral and bacterial infections, as well as non ...
John P Campbell, J. Turner
semanticscholar   +1 more source

Sexual dimorphism in the serum metabolome following acute exhaustive exercise

Biology of Sex Differences
Background Sex differences in exercise metabolism have been recognized for decades, but the molecular metabolic landscape in which men and women reach standardized physiological exhaustion criteria remains unexplored.
Baile Wu, Chunxue Tang, Zhongxun Ren, Jiayu Qian, Yuxiao Deng, Zihan Fan, YanYan Zhang, Lijun Shi   +7 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Cardiovascular Effects and Benefits of Exercise

Frontiers in Cardiovascular Medicine, 2018
It is widely accepted that regular physical activity is beneficial for cardiovascular health. Frequent exercise is robustly associated with a decrease in cardiovascular mortality as well as the risk of developing cardiovascular disease. Physically active
Matthew A. Nystoriak, A. Bhatnagar
semanticscholar   +1 more source

Repeat exercise normalizes the gas-exchange impairment induced by a previous exercise bout in asthmatic subjects [PDF]

, 2005
Twenty-one subjects with asthma underwent treadmill exercise to exhaustion at a workload that elicited approximately 90% of each subject's maximal O2 uptake (EX1).
Dempsey, JA, Eldridge, MW, Haverkamp, HC, Lovering, AT, Miller, JD, Pegelow, DF, Romer, LM   +6 more
core   +1 more source