Results 151 to 160 of about 1,331,726 (295)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Reproducibility of Computerized Measurements of QT Interval from Multiple Leads at Rest and During Exercise [PDF]

, 2006
Anna‐Mari Hekkala, Heikki Väänänen, Heikki Swan, Lasse Oikarinen, Matti Viitasalo, Lauri Toivonen   +5 more
openalex   +1 more source

Clinical efficacy of a personalized exercise program in the rehabilitation of patients with atrial fibrillation after radiofrequency ablation

, 2022
М. Г. Бубнова, Aronov Dm, M. M Makhinova, К. V. Davtyan   +3 more
openalex   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The Impact of High-Intensity Exercise in Normobaric Hypoxia on Right Ventricular Function in Trained and Untrained Men-An Echocardiographic Study. [PDF]

Compr Physiol
Robert G, Miłosz C, Kamila P, Ewa K, Adam N, Michał S, Natalia GZ, Katarzyna K, Józef L.   +8 more
europepmc   +1 more source

Acute effects of exercise timing and breakfast meal glycemic index on exercise-induced fat oxidation

, 2006
Patrick Bennard, Éric Doucet
openalex   +1 more source

Hormetic Property of Ginseng Steroids on Anti-Oxidant Status against Exercise Challenge in Rat Skeletal Muscle [PDF]

, 2017
Ming-Fen Hsu, Szu-Hsien Yu, Mallikarjuna Korivi, Wei-Horng Jean, Shin‐Da Lee, Chih‐Yang Huang, Yi-Hung Liao, Jessica Bo Li Lu, Chia‐Hua Kuo   +8 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Beyond Hormone Replacement: Multifaceted Effects of Phytoestrogens for Optimizing Kinesiological and Physiological Adaptations in Postmenopausal Women

Clinical Interventions in Aging
Yingjia Hu, Yi Hu, Tao Li, Rengfei Shi School of Health and Exercise, Shanghai University of Sport, Shanghai, People’s Republic of ChinaCorrespondence: Rengfei Shi, School of Health and Exercise, Shanghai University of Sport, Shanghai, People’s Republic ...
Hu Y, Hu Y, Li T, Shi R
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