Results 161 to 170 of about 4,484,039 (388)

Pricing American Options by Exercise Rate Optimization [PDF]

open access: yesarXiv, 2018
We present a novel method for the numerical pricing of American options based on Monte Carlo simulation and the optimization of exercise strategies. Previous solutions to this problem either explicitly or implicitly determine so-called optimal exercise regions, which consist of points in time and space at which a given option is exercised. In contrast,
arxiv  

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Effects of exercise training on cardiac output in subjects with heart failure with preserved ejection fraction (HFpEF) — a protocol for a systematic review and meta-analysis

open access: yesSystematic Reviews
Background Patients with heart failure with preserved ejection fraction (HFpEF) commonly experience exercise intolerance, resulting in reduced cardiorespiratory fitness.
Raphael Schoch   +4 more
doaj   +1 more source

Exercise and Depression

open access: yesEndocrinology and Metabolism, 2015
Depression is a chronic medical condition that can lead to serious functional impairment, morbidity, and mortality if left untreated [1,2]. Increasing awareness of depression as a significant public health problem has led to greater interest in both the underlying mechanisms and external factors associated with the disease, with therapies developed to ...
openaire   +4 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Intelligent Repetition Counting for Unseen Exercises: A Few-Shot Learning Approach with Sensor Signals [PDF]

open access: yesarXiv
Sensing technology has significantly advanced in automating systems that reflect human movement, particularly in robotics and healthcare, where it is used to automatically detect target movements. This study develops a method to automatically count exercise repetitions by analyzing IMU signals, with a focus on a universal exercise repetition counting ...
arxiv  

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