Depression is a common and important cause of morbidity and mortality worldwide. It is commonly treated with antidepressants and/or psychological therapy, but some people prefer alternative approaches such as exercise. There are a number of theoretical reasons why exercise may improve depression. This is an update of a review first published in 2009.
Cooney, G. M.+7 more
openaire +10 more sources
Impaired myocardial relaxation with exercise determines peak aerobic exercise capacity in heart failure with preserved ejection fraction [PDF]
Background Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by impaired exercise capacity due to shortness of breath and/or fatigue.
Abbate, Antonio+7 more
core +2 more sources
Exercise Increases Pressure Pain Tolerance but Not Pressure and Heat Pain Thresholds in Healthy Young Men [PDF]
Background: Exercise causes an acute decrease in the pain sensitivity known as exercise-induced hypoalgesia (EIH), but the specificity to certain pain modalities remains unknown.
Bartholomew+39 more
core +2 more sources
Statins, Exercise, and Exercise Training
Statins are life-saving medications and so effective that some have suggested they be added to the drinking water to “fluorinate” the vascular bed against atherosclerotic disease. But statins, both in research models and clinically, can have deleterious effects on skeletal muscle.
Beth A. Parker, Paul D. Thompson
openaire +3 more sources
Consumer Litigation Funding: Just Another Form of Payday Lending? [PDF]
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces permanent neurochemical and functional deficits. Following the administration of either two or four injections of the dopamine neurotoxin, MPTP, at a dose of 40 mg/kg, C57/BL6 mice were given ...
Archer, Trevor+2 more
core +3 more sources
Survivors Speak: A Qualitative Analysis of Motivational Factors Influencing Breast Cancer Survivors’ Participation in a Sprint Distance Triathlon [PDF]
Aims and Objectives To examine motivational factors influencing breast cancer survivors to participate in triathlon training, complete a triathlon and maintain an exercise thereafter.
Ng, Alexander V.+4 more
core +2 more sources
Appetite, gut hormone and energy intake responses to low volume sprint interval and traditional endurance exercise. [PDF]
Sprint interval exercise improves several health markers but the appetite and energy balance response is unknown. This study compared the effects of sprint interval and endurance exercise on appetite, energy intake and gut hormone responses.
A Flint+41 more
core +1 more source
Sestrins are evolutionarily conserved mediators of exercise benefits. [PDF]
Exercise is among the most effective interventions for age-associated mobility decline and metabolic dysregulation. Although long-term endurance exercise promotes insulin sensitivity and expands respiratory capacity, genetic components and pathways ...
Brooks, Susan V+14 more
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Exercise epigenetics and the foetal origins of disease [PDF]
Exercise epigenetics is a nascent area of research with vast health implications (e.g., from the treatment of obesity-related diseases to beneficially decoupling epigenetic and chronological age).
Dale E, Thomas EW Chalk, William M Brown
core +1 more source