Results 221 to 230 of about 4,484,039 (388)

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Cardiopulmonary responses to acute exogenous ketosis at rest, and during submaximal and maximal exercise. [PDF]

open access: yesPhysiol Rep
Crabtree CD   +14 more
europepmc   +1 more source

Normal Response Curve to Exercise of Relative Cardiac Output Measured with Radioiodinated Serum Albumin [PDF]

open access: bronze, 1959
Sylvan Lee Weinberg   +4 more
openalex   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Repair of the Anterior Horn of the Lateral and Medial Meniscus With Knotless Suture Anchor

open access: yesArthroscopy Techniques
The anterior horn lateral meniscus tear often is accompanied by perimeniscal cysts, which are treated with arthroscopic cyst excision with outside-in repair of the anterior horn. After cyst excision, there is a large gap between the thin anterior capsule
Milind V. Pimprikar, M.S.D. Ortho., P.G. Dip. Sports and Exercise Medicine   +1 more
doaj  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

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