Results 231 to 240 of about 5,869,609 (392)

Acute Exercise Induced Mitochondrial H₂O₂Production in Mouse Skeletal Muscle: Association with p^66Shcand FOXO3a Signaling and Antioxidant Enzymes [PDF]

, 2015
Ping Wang, Chun Guang Li, Zhengtang Qi, Di Cui, Shuzhe Ding   +4 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

To exercise or not to exercise

Low back pain (LBP) is a prevalent musculoskeletal condition that affects a large portion of the adult population globally, contributing to significant disability and economic burden. Clinical guidelines emphasize the biopsychosocial model for LBP management, which focuses on patient education, self-management, and interventions such as physical ...
openaire   +2 more sources

Effects of a Telephone-Based Exercise Intervention for Dementia Caregiving Wives

, 2008
Cathleen M Connell, Mary R. Janevic
openalex   +2 more sources

Fast regulation of the NF-κB signalling pathway in human skeletal muscle revealed by high-intensity exercise and ischaemia at exhaustion: Role of oxygenation and metabolite accumulation

, 2022
Ángel Gallego-Selles, Víctor Galván-Álvarez, Miriam Martinez‐Canton, Eduardo García-Gonzalez, David Morales‐Álamo, Alfredo Santana, Juan José González, Cecilia Dorado, José A. L. Calbet, Marcos Martín-Rincón   +9 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Mechanisms of Moral Disengagement in the Exercise of Moral Agency

, 1996
A. Bandura, C. Barbaranelli, G. Caprara, C. Pastorelli   +3 more
semanticscholar   +1 more source

Influence of brain catecholamines on the development of fatigue in exercising rats in the heat

, 2007
Hiroshi Hasegawa, Maria Francesca Piacentini, Sophie Sarre, Yvette Michotte, Takayuki Ishiwata, Romain Meeusen   +5 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source