Results 261 to 270 of about 4,230,796 (390)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Intra-breath respiratory mechanics of prematurity-associated lung disease phenotypes in school-aged children. [PDF]

ERJ Open Res
Cousins M, Hart K, Radics B, Henderson AJ, Hantos Z, Sly PD, Kotecha S.   +6 more
europepmc   +1 more source

The blood flow in the human arm during supine leg exercise

, 1957
J. M. Bishop, K. W. Donald, S. H. Taylor, P-J Wormald   +3 more
openalex   +2 more sources

EFFECT OF MUSCULAR EXERCISE UPON THE PERIPHERAL CIRCULATION IN PATIENTS WITH VALVULAR HEART DISEASE 1 [PDF]

, 1942
David I. Abramson, Sidney M. Fierst, Kamillo Flachs   +2 more
openalex   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Physical exercise and epigenetic modifications in skeletal muscle, brain, and heart. [PDF]

Epigenetics Chromatin
Zheng X, Liu X, Guo Y, Lv Y, Lin C, Wang D, Wang S, Liu Y, Hu X.   +8 more
europepmc   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Four-week Nordic hamstring exercise intervention for individuals with ACL reconstruction via hamstrings tendon autograft: feasibility of a pilot randomized controlled trial. [PDF]

Pilot Feasibility Stud
Norte GE, Glaviano NR, Sherman DA, Rush JL, Murray AM.   +4 more
europepmc   +1 more source

THE EFFECT OF EXERCISE ON THE SIZE OF NORMAL HEARTS AND OF ENLARGED HEARTS OF DOGS [PDF]

, 1929
Harold J. Stewart
openalex   +1 more source