Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Rationale and design of an exercise intervention for patients with cancer cachexia: protocol for a one-year follow-up prospective study (2CAPA). [PDF]
Peyrachon R+6 more
europepmc +1 more source
Hyperaemia following arterial occlusion or exercise in the warm and cold human forearm
D. R. Coles, Keith Cooper
openalex +2 more sources
THE RELATION OF EXERCISE TO BUBBLE FORMATION IN ANIMALS DECOMPRESSED TO SEA LEVEL FROM HIGH BAROMETRIC PRESSURES [PDF]
Morgan Harris+3 more
openalex +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Resistance Exercise as a Safe Modality for Quality of Life Improvement in Patients with Coronary Artery Diseases: A Review. [PDF]
Nazir A+6 more
europepmc +1 more source
RESYNTHESIS OF MUSCLE GLYCOGEN AFTER EXERCISE
Eunice V. Flock, Jesse L. Bollman
openalex +1 more source
LACTIC ACID PRODUCTION DURING REST AND AFTER EXERCISE IN SUBJECTS WITH VARIOUS TYPES OF HEART DISEASE WITH SPECIAL REFERENCE TO CONGENITAL HEART DISEASE 1 [PDF]
Phillip Hallock
openalex +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Exercise-induced metabolomics and its association with metabolic health in adolescents. [PDF]
Guo X+12 more
europepmc +1 more source