Results 41 to 50 of about 979,425 (244)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Physiological Impacts of the Low- and Moderate-Volume-HIIT with or without Nano-Curcumin Supplement in Women in Menopause with Obesity

Advances in Public Health
Tabata exercise has been proposed as an extremely time-efficient high-intensity interval training (HIIT) method to achieve health benefits, but direct comparisons between the low-volume-HIIT (LV-HIIT), moderate-volume-HIIT (MV-HIIT) with and without nano-
Valiollah Dabidi Roshan, Sepideh Noorbakhsh, Seyedeh Fatemeh Ziatabar Ahmadi, Mehdi Nikseresht   +3 more
doaj   +1 more source

Protocol for a systematic review and meta-analysis of observational studies examining the impact of COVID-19 safety measures on physical activity patterns in adults

Systematic Reviews, 2021
Background The primary objective of this study is twofold: (1) to examine the effect of COVID-19 safety measures, enacted to prevent transmission of SARS-nCOV-2, on total physical activity in the adult general population (≥ 18 years) and (2) to analyze ...
Fabian Schwendinger, Denis Infanger, Elena Pocecco, Joséphine Gander, Timo Hinrichs, Arno Schmidt-Trucksäss   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Effect of Midsole Thickness on Running Economy, Spatiotemporal Values and Perceptions of Comfort and Exertion in Well-trained Runners: A Randomized, Cross-over Trial

Sports Medicine - Open
Background Distance running has been revolutionised by the introduction of modern running shoes, named advanced footwear technology (AFT). AFT shoes commonly implement carbon fibre plates to increase longitudinal bending stiffness as well as highly ...
Gian-Andri Baumann, Kai Biedermann, Enea Item, Christina M. Spengler, Fernando Gabe Beltrami   +4 more
doaj   +1 more source

Effects of Compression Pants with Different Pressure Levels on Anaerobic Performance and Post-Exercise Physiological Recovery: Randomized Crossover Trial

Sensors
Compression pants, as functional sportswear providing external pressure, are widely used to enhance athletic performance and accelerate recovery. However, systematic investigations into their effectiveness during anaerobic exercise and the impact of ...
Qinlong Li, Kaixuan Che, Wenlang Yu, Wenda Song, Yue Zhou   +4 more
doaj   +1 more source

Functional assessments of foot strength: a comparative and repeatability study

BMC Musculoskeletal Disorders, 2019
Background Evaluating the strength of the small muscles of the foot may be useful in a variety of clinical applications but is challenging from a methodology standpoint.
Dustin A. Bruening, Sarah T. Ridge, Julia L. Jacobs, Mark T. Olsen, Dallin W. Griffin, Drew H. Ferguson, Kirk E. Bassett, A. Wayne Johnson   +7 more
doaj   +1 more source

High-speed resistance training and balance training for people with knee osteoarthritis to reduce falls risk: study protocol for a pilot randomized controlled trial

Trials, 2017
Background The number of falls experienced by people with knee osteoarthritis (OA) is almost double the number experienced by people with no OA. The neuromuscular elements required to arrest a fall are more impaired in people with knee OA compared to ...
Pazit Levinger, Jeremy Dunn, Nancy Bifera, Michael Butson, George Elias, Keith D. Hill   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source