Results 71 to 80 of about 2,030,110 (298)

Juvenile vs. adult skeletal muscle transplants in the treatment of volumetric muscle loss injury

Stem Cell Research & Therapy
Background Volumetric muscle loss (VML) causes irreversible structural and functional deficits by removing myofibers, nerves, vasculature, extracellular matrix, and satellite cells, the resident muscle stem cells essential for regeneration.
John J. Payne, Samuel R. Frandsen, Zachary H. Rasmussen, Matthew J. Mangus, Anna C. Taylor, Mason K. Kephart, Sandy S. Huang, Thomas K. Schiefer, Kyndal M. Jones, Erastus W. Evans, Jacob R. Sorensen   +10 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Acute Post-Exercise Blood Pressure Responses in Middle-Aged Persons with Elevated Blood Pressure/Stage 1 Hypertension following Moderate and High-Intensity Isoenergetic Endurance Exercise [PDF]

, 2020
International Journal of Exercise Science 13(3): 1532-1548, 2020.This study investigated the acute post-exercise hypotension (PEH) response in persons with elevated blood pressure or stage 1 hypertension following moderate and high-intensity isoenergetic
Olsrud, Marianne, Berge, Hanna, Gjøvaag, Terje, Welde, Boye   +3 more
core  

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Bioengineered model of the human motor unit with physiologically functional neuromuscular junctions

Scientific Reports, 2021
Investigations of the human neuromuscular junction (NMJ) have predominately utilised experimental animals, model organisms, or monolayer cell cultures that fail to represent the physiological complexity of the synapse.
Rowan P. Rimington, Jacob W. Fleming, Andrew J. Capel, Patrick C. Wheeler, Mark P. Lewis   +4 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Extended field-of-view ultrasound imaging is reliable for measuring Transversus Abdominis muscle size at rest and during contraction

BMC Musculoskeletal Disorders, 2021
Background The strength and size of core muscles, including the abdominal muscles, are crucial to proper function in most activities. Therefore, it is important to reliably assess these characteristics.
A. Wayne Johnson, Lauren Adams, Jade B. Kho, Daniel M. Green, Nicolas B. Pace, Ulrike H. Mitchell   +5 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

The Physiological Impacts of the Low- and Moderate-Volume-HIIT with or without Nano-Curcumin Supplement in Women in Menopause with Obesity

Advances in Public Health
Tabata exercise has been proposed as an extremely time-efficient high-intensity interval training (HIIT) method to achieve health benefits, but direct comparisons between the low-volume-HIIT (LV-HIIT), moderate-volume-HIIT (MV-HIIT) with and without nano-
Valiollah Dabidi Roshan, Sepideh Noorbakhsh, Seyedeh Fatemeh Ziatabar Ahmadi, Mehdi Nikseresht   +3 more
doaj   +1 more source

Trends in body image of adolescent females in metropolitan and non-metropolitan regions: a longitudinal study

BMC Public Health, 2016
Background Body dissatisfaction is associated with a range of adverse outcomes, including impaired psychological health, low physical activity and disordered eating.
M. Craike, J. A. Young, C. M. Symons, M. D. Pain, J. T. Harvey, R. M. Eime, W. R. Payne   +6 more
doaj   +1 more source