Results 111 to 120 of about 617,106 (283)

Profiling and assessing the risks of image- and performance-enhancing drugs use during the COVID-19 lockdown

Frontiers in Public Health
BackgroundImage and Performance-Enhancing Drugs (IPEDs) can enhance mental and physical capabilities and impact one’s overall health. Initially confined in sport environments, IPEDs use has become increasingly widespread in a high-performing society. The
Ilaria De Luca, Francesco Di Carlo, Julius Burkauskas, Artemisa R. Dores, Artemisa R. Dores, Irene P. Carvalho, M. Ángeles Gómez-Martínez, Attila Szabo, Attila Szabo, Hironobu Fujiwara, Hironobu Fujiwara, Hironobu Fujiwara, Cristina Monteiro Barbosa, Marco Di Nicola, Marianna Mazza, Gabriele Sani, Debora Luciani, Mauro Pettorruso, Massimo di Giannantonio, Ilaria Cataldo, Gianluca Esposito, Giovanni Martinotti, Giovanni Martinotti, Thomas Zandonai, Olivier Rabin, Olivier Rabin, Ornella Corazza, Ornella Corazza   +27 more
doaj   +1 more source

Effects of curative treatment emphasizing endurance training on the performance and blood pressure of hypertensive and normotensives [PDF]

The problem of normal values of blood pressure after exercise taking into account the blood pressure at the end of the exercise test is discussed. Hypertensives showed a lower working capacity than normotensives. In normotensives, however, systolic blood
Worms, F.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Meta-analysis on intervention effects of exercise on Chinese children and adolescents with mobile phone dependence

Frontiers in Psychology
ObjectiveThis study aims to examine which exercise regimens may have a stronger intervention effect and assess the impact of exercise on children’s and teenagers’ dependence on mobile phones using a meta-analysis system.MethodsFrom the library’s founding
Long Chen, Yilin Ren, Pingting Zhu, Yahui Yang, Fengshu Zhu   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Prevalence and Association of Exercise Dependence and Eating Disorder Risk in Collegiate Student-Athletes. [PDF]

J Athl Train, 2023
Uriegas NA, Moore K, Torres-McGehee TM.
europepmc   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Chinese version of exercise dependence scale-revised: psychometric analysis and exploration of risk factors. [PDF]

Front Psychol, 2023
Shao Y, Zhang H, Zhang X, Liang Q, Zhang H, Zhang F.   +5 more
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source