Results 281 to 290 of about 1,276,748 (319)
Toward a working definition of ketogenic diet resistance in GLUT1 deficiency syndrome
Abstract Objective The ketogenic diet (KD) is the standard treatment for glucose transporter type 1 deficiency syndrome (GLUT1‐DS), typically yielding seizure reduction and cognitive/motor gains. However, a small subset of patients shows limited or no clinical benefit.
Raffaele Falsaperla +8 more
wiley +1 more source
Mitochondria Transplantation: Rescuing Innate Muscle Bioenergetic Impairment in a Model of Aging and Exercise Intolerance. [PDF]
Arroum T +11 more
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola +3 more
wiley +1 more source
Opposite kinetics of L-leucine and L-phenylalanine induced insulin release studies with the perfused rat pancreas [PDF]
Landgraf, R. +3 more
core
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
ABSTRACT Objective Psychiatric comorbid conditions are common among individuals with Eating Disorders (EDs), and these symptoms may exacerbate and/or interact with ED symptoms and impact treatment effectiveness. Whilst comorbid symptomology in Anorexia Nervosa (AN) has been well described, less is known about how the ‘newer’ ED diagnoses of Atypical ...
Daniel Wilson +5 more
wiley +1 more source

