Results 361 to 370 of about 16,275,044 (430)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Validation of the maximal cardiopulmonary exercise test in adolescents with major depressive disorder and comparison of cardiorespiratory fitness with sex- and age-related control values. [PDF]

open access: yesEur J Pediatr
Wenzel C   +10 more
europepmc   +1 more source

Exercise stress testing

Medical Journal of Australia, 1984
Before performing stress testing, it is necessary to have a clear understanding of what question one wishes to answer. Although the exercise stress test can provide useful information to guide the physician in the management of patients, awareness of the limitations of this procedure and of the need for a probability approach to its interpretation is ...
A A Carr, L M Prisant, L O Watkins
  +9 more sources

Exercise prescription

A Practical Guide to the Interpretation of Cardiopulmonary Exercise Tests, 2021
This chapter outlines the health benefits of exercise. A cardiopulmonary exercise test (CPET) can reassure the subject that exercise is safe for them. Exercise can be prescribed using heart rate zones derived from the CPET.
W. Kinnear, James H. Hull
semanticscholar   +1 more source

PERFORMING THE EXERCISE TEST

Primary Care: Clinics in Office Practice, 1994
Exercise testing is useful in assessing physical fitness, determining functional capacity, diagnosing ischemic heart disease, defining the prognosis of ischemic heart disease, developing an exercise prescription, and guiding cardiac rehabilitation. This article outlines the current indications, contraindications, and special considerations for exercise
Corey H. Evans, Russell D. White
openaire   +4 more sources

Test-Retest Reliability of a Modified Visual Analog Scale Assessment Tool for Determining Incidence and Severity of Gastrointestinal Symptoms in Response to Exercise Stress.

International Journal of Sport Nutrition & Exercise Metabolism, 2019
Considering the recent growth of exercise gastroenterology research focusing on exercise-induced gastrointestinal syndrome mechanisms, response magnitude, prevention and management strategies, the standardized assessment of gastrointestinal symptoms (GIS)
S. Gaskell   +2 more
semanticscholar   +1 more source

Magnetocardiography and exercise testing

Journal of Electrocardiology, 1994
Twenty healthy male subjects (age range, 15-25 years; median, 21 years) underwent magnetocardiography during physical exercise. Significant ST-segment displacements of the magnetic signal were found during exercise at a heart rate of 120 beats/min compared to the magnetic signal at rest (P < .001).
BROCKMEIER C   +5 more
openaire   +4 more sources

Exercise testing in pediatrics [PDF]

open access: possiblePediatric Clinics of North America, 2004
This article discusses exercise physiology and its application in the pediatric population. This article discusses exercise physiology and its application in the pediatric population. The authors briefly review the normal physiologic response to exercise.
Paul Stephens   +2 more
openaire   +2 more sources

Patterning of affective responses during a graded exercise test in children and adolescents.

Pediatric Exercise Science, 2012
Past studies have shown the patterning of affective responses during a graded exercise test (GXT) in adult and male adolescent populations, but none have explored the patterns in adolescent girls or younger children. This study explored the patterning of
C. Benjamin, A. Rowlands, G. Parfitt
semanticscholar   +1 more source

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