Results 41 to 50 of about 16,395,796 (358)

Home-based or remote exercise testing in chronic respiratory disease, during the COVID-19 pandemic and beyond: A rapid review

medRxiv, 2020
Objectives: To identify exercise tests that are suitable for home-based or remote administration in people with chronic lung disease. Methods: Rapid review of studies that reported home-based or remote administration of an exercise test in people with ...
A. Holland, C. Malaguti, M. Hoffman, A. Lahham, A. Burge, Leona M. Dowman, A. May, J. Bondarenko, M. Graco, G. Tikellis, J. Lee, N. Cox   +11 more
semanticscholar   +1 more source

Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors

Population Ecology, EarlyView.
Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Exercise Increases Pressure Pain Tolerance but Not Pressure and Heat Pain Thresholds in Healthy Young Men [PDF]

, 2017
Background: Exercise causes an acute decrease in the pain sensitivity known as exercise-induced hypoalgesia (EIH), but the specificity to certain pain modalities remains unknown.
Bartholomew, Chong, Cook, Fleiss, Graven-Nielsen, Graven-Nielsen, Greenspan, Grone, Hoeger Bement, Hoeger Bement, Hoeger Bement, Hoeger Bement, Kodesh, Koltyn, Koltyn, Koltyn, Koltyn, Kosek, Kosek, Kosek, Lannersten, Leffler, Lemley, Lemley, Mannerkorpi, Misra, Naugle, Neziri, Nussbaum, Ohrbach, Oono, Polianskis, Popescu, Tuveson, Umeda, Umeda, Vaegter, Vaegter, Vaegter, Yu   +39 more
core   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Wearing colored glasses can influence the exercise performance and testosterone concentration [PDF]

, 2018
Perception of red color is associated with higher testosterone concentration and better human performance. Thus, we evaluated the acute effects of wearing colored-lens glasses on the YoYo intermittent endurance exercise test 2 (YoYoIE2) performance ...
Campos Souza, Markus Vinicius, Fisher, James, Lande, Andre M., Marocolo, Isabela Coelho, Marocolo, Moacir, Neto, Octavio Barbosa, Ribeiro da Mota, Gustavo   +6 more
core   +1 more source

Impact of Active Recovery and Whole-Body Electromyostimulation on Blood-Flow and Blood Lactate Removal in Healthy People [PDF]

, 2020
This study aimed to determine whether an active recovery with added whole-body electromyostimulation (WB-EMS) can increase blood flow and lead to blood lactate removal after intense exercise.
Babault, Barnett, Bieuzen, Borne, Currier, de la Camara Serrano, Dupuy, Erten, Griffin, Hopkins, Kaplan, Kastner, Kemmler, Kemmler, Kemmler, Kuipers, Lattier, Malone, Martin, Menendez, Neric, Nosaka, Pano-Rodriguez, Sheriff, Signorile, Toubekis, Tucker, Vanderthommen, Williams   +28 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source