Results 81 to 90 of about 732,546 (337)

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Utilização do teste de caminhada de 6 minutos no manejo da hipertensão pulmonar Utilización del test de caminata de 6 minutos en el manejo de la hipertensión pulmonar Use of 6-minute walk test in pulmonary hypertension management

open access: yesArquivos Brasileiros de Cardiologia, 2010
O teste de caminhada de 6 minutos (T6) é utilizado na avaliação de doenças cardiopulmonares por sua capacidade prognóstica, facilidade de realização e reprodutibilidade.
Elize Fumagalli   +3 more
doaj  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Evaluation of Different Dyspnea Scales in Smokers with Preserved FEV1/FVC Ratio [PDF]

open access: yesInternational Journal of Biomedicine
Background: This study evaluated the relationships between two dyspnea scales (Modified Borg Scale [MBS] and modified Medical Research Council dyspnea scale [mMRCds]) and clinical characteristics of smokers with preserved FEV1/FVC ratio. It also assessed
Besim Morina   +3 more
doaj   +1 more source

The Nitroglycerin Exercise Test

open access: yesCardiology, 1981
The nitroglycerin (NTG) exercise test can help in detecting ischemia in the presence of right bundle branch block (RBBB), left bundle branch block (LBBB), or digitalis-induced exercise ST changes and in excluding ischemia when a falsely positive test is suspected.
Linda R. Carroll, Lenore R. Zohman
openaire   +3 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

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