Results 81 to 90 of about 603,898 (307)

Cardiopulmonary exercise testing is a better outcome predictor than exercise echocardiography in asymptomatic aortic stenosis [PDF]

open access: bronze, 2016
Olivia Domanski   +9 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Predicting Heart Rate Slow Component Dynamics: A Model Across Exercise Intensities, Age, and Sex

open access: yesSports
The heart rate slow component (scHR) is an intensity-dependent HR increment that emerges during constant exercises, partially dissociated from metabolism (V˙O2).
Massimo Teso   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Intra- and inter-rater reproducibility of the 6-minute walk test and the 30-second sit-to-stand test in patients with severe and very severe COPD

open access: yesInternational Journal of COPD, 2018
Henrik Hansen,1 Nina Beyer,2 Anne Frølich,1 Nina Godtfredsen,2,3 Theresa Bieler4 1Research Unit of Chronic Diseases and Telemedicine – Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg University Hospital, Copenhagen,
Hansen H   +4 more
doaj  

Assessment of Beep Test Performance and Cardiorespiratory Endurance in Young Footballers: A Cross-sectional Study in the UAE

open access: yesDubai Medical Journal
Aim: The study aims to examine the Beep test performance and the cardiorespiratory endurance among young footballers in the United Arab Emirates while also analyzing the correlations of lower limb muscle strength (quadriceps, hamstrings, and calf muscle)
Shahwar Fatima Ansari   +8 more
doaj   +1 more source

Rapid determination of the hypoxanthine increase in ischemic exercise tests. [PDF]

open access: bronze, 1988
P. A. Bolhuis   +4 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Assessment of Physical Performance in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy Evaluated by Cardiopulmonary Exercise Testing – A Long-Term Follow-Up Study

open access: green, 2023
Robin Willixhofer   +8 more
openalex   +1 more source

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