Results 71 to 80 of about 6,235 (213)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Difference in out-of-school physical activity patterns, sedentary behavior, and health-related fitness in relation to mathematics achievement among school-aged children: a cross-sectional study

Frontiers in Education
AimThis study examined differences in health-related fitness, physical activity patterns, and sedentary behavior among Qatari schoolchildren, classified by their mathematics achievement levels.MethodsNinety-eight schoolchildren (age: 12.1 ± 0.5 years ...
Souhail Hermassi, Wissem Dhahbi, Wissem Dhahbi, Nidhal Jebabli, Abdulla Alneama, Sascha Ketelhut, Roland van den Tillaar   +6 more
doaj   +1 more source

Forced Swim Reliability for Exercise Testing in Rats by a Tethered Swimming Apparatus

Frontiers in Physiology, 2018
To assess the physical capacity of rats in forced swim tests, the animal should perform a continuous activity (CON) at the surface to avoid apnea. Bobbing movement (BOB), vigorous paddling known as climbing (CLI), and diving activity (DIV) are inadequate
Ivan G. M. dos Reis, Luiz E. B. Martins, Gustavo G. de Araujo, Claudio A. Gobatto   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Meta-analyses in sport and exercise science: sometimes the right tool at the wrong time?

Systematic Reviews
Background Meta-analysis is widely regarded as a high-level form of evidence in scientific research, particularly in the medical and life sciences. In sport and exercise science, the number of published meta-analyses has increased rapidly in recent years.
Sebastian Puschkasch-Möck, José Afonso, Konstantin Warneke, Klaus Wirth   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reduced Variability of Endurance Time in New Protocols for Exercise Tests in COPD

International Journal of COPD, 2020
Ellen Tufvesson,1 Finn Radner,1 Georgia Papapostolou,1 Linnea Jarenbäck,1 Saga Jönsson,1 Ulf Nihlén,1 Jaro Ankerst,1 Alf Tunsäter,1 Stefan Peterson,2 Leif Bjermer,1 Göran Eriksson1 1Department of Clinical Sciences Lund ...
Tufvesson E, Radner F, Papapostolou G, Jarenbäck L, Jönsson S, Nihlén U, Ankerst J, Tunsäter A, Peterson S, Bjermer L, Eriksson G   +10 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source