Results 201 to 210 of about 981,197 (361)

Closing GDMT Gaps in PAD Patients During Supervised Exercise Therapy. [PDF]

JACC Case Rep
Muir SM, Albers AR.
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Response to exercise in patients with pulmonary arterial hypertension treated with combination therapy [PDF]

, 2020
Mari Nishizaki, Aiko Ogawa, Hiromi Matsubara   +2 more
openalex   +1 more source

Electromyographic examination of a new exercise therapy for the intrinsic and extrinsic foot muscles. [PDF]

J Phys Ther Sci
Kuroyanagi E, Watanabe T, Furusawa H, Tsutsumi M, Kudo S.   +4 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Prognostic Value of Conventional Ultrasound and MRI Features for Clinical Outcomes in Athletes With Patellar Tendinopathy After Exercise Therapy. [PDF]

Sports Health
Deng J, Breda SJ, Fang Y, Eygendaal D, de Vos RJ, Oei EHG.   +5 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

<p>Evaluation of Hypoglycemic Therapy Through Physical Exercise in n5STZ-Induced Diabetes Rats</p> [PDF]

, 2020
J. K. C. Ribeiro, TV Nascimento, A Agostinho, Raquel Martins de Freitas, LHP Santos, LMQ Machado, José Henrique Leal‐Cardoso, MD Moreira-Gomes, Vânia Marilande Ceccatto   +8 more
openalex   +1 more source

Individualized online exercise therapy aids recovery in pediatric long-COVID-findings from an exploratory randomized controlled trial. [PDF]

Eur J Pediatr
Goretzki SC, Bergelt M, Weis L, Hojeii R, Gauß G, Götte M, Beller R, Benson S, Schönecker A, Marina AD, Gangfuß A, Stehling F, Pentek C, von Loewenich A, Hühne T, Held C, Voigt S, Felderhoff-Müser U, Schündeln MM, Bruns N, Eckert K, Dohna-Schwake C, Brasseler M.   +22 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source