Results 121 to 130 of about 347,819 (383)
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Run to the Beat: Sport and music for the masses [PDF]
, 2013 Run to the Beat is a half marathon event that is accompanied by live and pre-recorded music. The author was involved with the event as the lead consultant in the period 2007-2010. This case study examines the genesis of the event, the science on which it
Karageorghis, CI
core +1 more source
Technologies in Exertion Games [PDF]
, 2013 Introduction Sports and technology have a long history of merging together fruitfully. For example, technology has been very successful in offering sports people better and more nuanced feedback of their athletic performance. Advancements in sensor technology have been providing athletes with information about their abilities, skills and achievements ...
openaire +2 more sources
The fever of over-exertion [PDF]
Transactions of the Royal Academy of Medicine in Ireland, 1888 n ...
openaire +3 more sources
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Blood lipid associations in 18 year-old men
Revista de Saúde PúblicaThe association of cigarette smoking, physical activity at work, and social class with total cholesterol and with high and low density lipoprotein cholesterol were examined in a random sample of 238 males, of 18 years of age, of Rosario, Argerntina.
Leonor Poletto +2 more
doaj
Effort and the Standard Story of Action [PDF]
, 2012 In this paper, I present an alternative account of action that improves upon what has come to be known as the standard story. The standard story depicts actions as events that are caused by and made intelligible through the appropriate combinations of ...
Brent, Michael
core
Some effects of high air temperatures and muscular exertion upon colliers [PDF]
, 1923 K. Nevillie Moss
openalex +1 more source
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source