Results 141 to 150 of about 347,819 (383)
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
THE RELATIONSHIP BETWEEN MUSCULOSKELETAL STRENGTH, PHYSIOLOGICAL CHARACTERISTICS, AND KNEE KINESTHESIA FOLLOWING FATIGUING EXERCISE [PDF]
, 2012 Fatiguing exercise may result in impaired functional joint stability and increased risk of unintentional injury. While there are several musculoskeletal and physiological characteristics related to fatigue onset, their relationship with proprioceptive ...
Abt, John P +6 more
core
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
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Revista Brasileira de Cineantropometria e Desempenho Humano, 2014 The mechanisms and concepts of perceived exertion have changed over the years. Thus, the objectives of the present literature review were i) to investigate the literature reviews that have been published since 1982 and to describe the proposed causal ...
Gleber Pereira +3 more
doaj
Research Progress on the Trait of Stigma Exsertion in Rice
PlantsAs global food demand continues to grow, enhancing rice seed-setting rate and yield has emerged as a crucial research topic. The stigma exsertion rate in rice, a pivotal determinant of the outcrossing seed-setting rate in sterility lines, is essential ...
Hongming Guo +5 more
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Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Effects of Physical Training on Exertional S-T-Segment Depression in Coronary Heart Disease [PDF]
, 1971 Jean-Marie R. Detry, Robert A. Bruce
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Perceived exertion as an indicator of somatic stress.
Scandinavian Journal of Rehabilitation Medicine, 2019 G. Borg
semanticscholar +1 more source