Results 71 to 80 of about 347,819 (383)

Early-Morning and Late-Night Maximal Runs: Metabolic and Perceived Exertion Outcomes

open access: yes, 2020
People may exercise at the ends of their day to fit activity into their schedule; the purpose of this investigation was to determine if metabolic or perceived exertion outcomes differed between maximal runs early in the morning and late at night.
Carducci, Jenna L   +6 more
core  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Basketball Fatigue Impact on Kinematic Parameters and 3-Point Shooting Accuracy: Insights across Players’ Positions and Cardiorespiratory Fitness Associations of High-Level Players

open access: yesSports
This study investigated the impact of basketball-induced fatigue on 3-point jump shooting accuracy, the ball’s entry angle (EA) into the hoop, shot release time (RT), their relationship with player positions in high-level basketball, and the correlation ...
Dimitrios I. Bourdas   +5 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Exertional heat illness: international military-oriented lessons learned and best practices for prevention and management

open access: yesFrontiers in Physiology
Climate change has resulted in more frequent and intense heat waves, leading to elevated global temperatures and posing a significant health threat to individuals working in hot environments such as military personnel.
Yoram Epstein   +15 more
doaj   +1 more source

Attentional distraction during exercise in overweight and normal-weight boys [PDF]

open access: yes, 2015
The purpose of this study was to investigate the effect of attentional distraction on field running distance and activity intensity during an exercise session in normal-weight and overweight youngsters and to investigate potential mediators.
De Bourdeaudhuij, Ilse   +1 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Whole-Exome Molecular Autopsy After Exertion-Related Sudden Unexplained Death in the Young

open access: yesCirculation: Cardiovascular Genetics, 2016
Background— Targeted postmortem genetic testing of the 4 major channelopathy-susceptibility genes (KCNQ1, KCNH2, SCN5A, and RYR2) have yielded putative pathogenic mutations in ⩽30% of autopsy-negative sudden unexplained death in the young (SUDY) cases ...
Jason H. Anderson   +3 more
semanticscholar   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

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