Results 1 to 10 of about 15,308 (193)

Transforming growth factor β1, matrix metalloproteinase-2 and its tissue inhibitor in patients with pseudoexfoliation glaucoma/syndrome [PDF]

Vojnosanitetski Pregled, 2012
Background/Aim. Transforming growth factor-b1 (TGF-b1), oxidative stress and imbalance between matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) may play an important role in pathogenesis of pseudoexfoliation syndrome/glaucoma (PEX ...
Đorđević-Jocić Jasmina, Zlatanović Gordana, Veselinović Dragan, Jovanović Predrag, Djordjević Vidosava, Zvezdanović Lilika, Stanković-Babić Gordana, Vujanović Milena, Cekić Sonja, Zenkel Matthias, Schlotzer-Schrehardt Ursula   +10 more
doaj   +1 more source

Genome-Wide RNA Sequencing of Human Trabecular Meshwork Cells Treated with TGF-β1: Relevance to Pseudoexfoliation Glaucoma

Biomolecules, 2022
Pseudoexfoliation glaucoma (XFG) is an aggressive form of secondary open angle glaucoma, characterised by the production of exfoliation material and is estimated to affect 30 million people worldwide.
Anton W. Roodnat, Breedge Callaghan, Chelsey Doyle, Megan Henry, Katarzyna Goljanek-Whysall, David A. Simpson, Carl Sheridan, Sarah D. Atkinson, Colin E. Willoughby   +8 more
doaj   +1 more source

Hyaluronan in the exfoliation syndrome [PDF]

Acta Ophthalmologica Scandinavica, 1997
AbstractPurpose: To histochemically analyze if the glycoseaminoglycan component of pseudoexfoliation material consists of hyaluronan.Methods: The hyaluronan binding region of cartilage proteoglycans was utilized in a staining specific for hyaluronan. The technique has been described and employed previously.
T D, Fitzsimmons, P, Fagerholm, O, Wallin   +2 more
openaire   +2 more sources

A study of preoperative, intraoperative and postoperative complications of pseudoexfoliation syndrome in Indian eyes undergoing cataract surgery [PDF]

Al Ameen Journal of Medical Sciences, 2023
Objectives: To study the clinical profile and complications encountered in the management of cataract patients with pseudo exfoliation syndrome (PXF). Method: A cross sectional hospital based study was done on 50 eyes of 50 patients in a tertiary care ...
Vybhavi P. Kaushik, Madhu A. Gannur, Z.A. Golewale, Anand G. Gannur, Ayesha Batool   +4 more
doaj  

Increased concentration of tumour necrosis factor alpha in the plasma of glaucoma patients [PDF]

Vojnosanitetski Pregled
Background/Aim. Changes in the concentration of various mediators of inflammation in blood, aqueous humor, or eye tissues support the role of inflammation in the pathogenesis of open-angle glaucoma (OAG).
Trenkić Marija, Jevtović-Stoimenov Tatjana, Bašić Jelena, Vasilijević Jelena, Ristić Dragana, Trenkić Milan, Veselinović Aleksandar, Cvetanović Marija   +7 more
doaj   +1 more source

Transient expression of Wnt5a elicits ocular features of pseudoexfoliation syndrome in mice.

PLoS ONE, 2019
PURPOSE:Pseudoexfoliation (PEX) syndrome is an age-related systemic disease with ocular manifestations. The development of animal models is critical in order to elucidate the cause of the disease and to test potential treatment regimens.
Yong Yuan, Ursula Schlötzer-Schrehardt, Robert Ritch, Mindy Call, Fred B Chu, Fei Dong, Taylor Rice, Jianhua Zhang, Winston W-Y Kao   +8 more
doaj   +1 more source

Directed Therapy for Exfoliation Syndrome [PDF]

The Open Ophthalmology Journal, 2009
Exfoliation syndrome (XFS) is an age-related disorder of the extracellular matrix that leads the production of abnormal fibrillar material that leads to elevated intraocular pressure and a relatively severe glaucoma. Exfoliation material is deposited in numerous ocular tissues and extraocular organs.
Angelilli, Allison, Ritch, Robert
openaire   +3 more sources

Exfoliation syndrome.

Journal of the Formosan Medical Association = Taiwan yi zhi, 1997
Increasing pathophysiologic evidence indicates that exfoliation syndrome, a systemic process involving various visceral organs, frequently manifests itself first in the eyes as exfoliation of the lens and glaucoma. Exfoliation syndrome occurs when several tissues synthesize an abnormal basement membrane protein. This protein may obstruct the trabecular
Y J, Lin, T H, Wang, S C, Kao, P T, Hung
openaire   +1 more source

Risk factors for exfoliation glaucoma - Current evidence and perspectives

Indian Journal of Ophthalmology
Exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) represent a complex matrix of ocular age-related neurodegenerative changes. Numerous decades of research on this disease entity have highlighted the unique clinical features of ocular protein ...
Aparna Rao
doaj   +1 more source

Serum heparan sulfate and chondroitin sulfate concentrations in patients with newly diagnosed exfoliative glaucoma [PDF]

PeerJ, 2019
Background Exfoliative glaucoma (XFG) is typically classified as a high-pressure type of secondary open-angle glaucoma that develops as a consequence of exfoliation syndrome (XFS).
Vesna D. Maric, Marija M. Bozic, Andja M. Cirkovic, Sanja Dj Stankovic, Ivan S. Marjanovic, Anita D. Grgurevic   +5 more
doaj   +2 more sources