Results 91 to 100 of about 2,508,923 (191)
Scientific ReportsAmyloid-β (Aβ) accumulation is a well-established cause of neurotoxicity in the brain and a major factor in Alzheimer’s disease. However, its role in ocular neurodegeneration remains unclear.
Tsutomu Ohashi +6 more
doaj +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.ER stress could cause the O‐glycosylation of E‐cadherin in RTECs, leading to dysregulation of cell polarity and proliferation. ER stress inhibitors alleviate kidney injury and promote the recovery of kidney function. These findings provide new molecular targets and intervention strategies for the clinical treatment of AKI. ABSTRACT The loss of polarity
Yingjia Zhang +6 more
wiley +1 more source
Journal of glaucoma, 2020 Precis: Although peripapillary retinal nerve fiber layer thickness (RNFLTs) and vessel density (VD) values were similar to healthy group, eyes with exfoliation syndrome had significantly lower superficial macular VDs and minimum ganglion cell analysis ...
Sirel Gür Güngör +4 more
semanticscholar +1 more source
Unilateral ductus deferens aplasia with terminal cystic dilation in a Bernese mountain dog
Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.Abstract An incidental caudal abdominal mass was discovered in a 5‐year‐old, male, entire Bernese mountain dog. Investigations showed a terminal cystic dilation of the left ductus deferens. Castration, along with surgical resection of the mass, was performed, and histopathology of the mass and ductus deferens was consistent with segmental aplasia of ...
Daisy Johnson +3 more
wiley +1 more source
Experimental Models of Autoimmune Hepatitis: Disease Fidelity and Translational Relevance
Liver International, Volume 46, Issue 8, August 2026.ABSTRACT Autoimmune hepatitis (AIH) remains difficult to study mechanistically in patients because disease initiation is rarely observed directly, the relevant autoantigens differ across subsets, and clinically meaningful outcomes such as chronic inflammation, fibrosis, relapse, and treatment response evolve over time.
Laura Elisa Buitrago‐Molina +1 more
wiley +1 more source
Risk factors for exfoliation glaucoma - Current evidence and perspectives
Indian Journal of OphthalmologyExfoliation syndrome (XFS) and exfoliation glaucoma (XFG) represent a complex matrix of ocular age-related neurodegenerative changes. Numerous decades of research on this disease entity have highlighted the unique clinical features of ocular protein ...
Aparna Rao
doaj +1 more source
Phenobarbital‐Induced Toxic Epidermal Necrolysis: A Case Report
Clinical Case Reports, Volume 14, Issue 7, July 2026.ABSTRACT Adverse drug reactions (ADRs) can lead to severe consequences and increased morbidity and mortality rates. Phenobarbital is one of the most common anti‐epileptic drugs that has numerous adverse drug reactions, including toxic epidermal necrolysis. The event is rare and a medical emergency.
Biniyam Tedla Mamo +8 more
wiley +1 more source
Nature Genetics, 2017 Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, have previously been associated with XFS. To further elucidate the genetic basis of
T. Aung +288 more
semanticscholar +1 more source
A study of the angle of anterior chamber in exfoliation syndrome
Journal of Clinical Ophthalmology and Research, 2018 Introduction: Exfoliation syndrome (ES) is associated with a variety of findings in the angle of the anterior chamber of the eyes. We undertook the present study to record such findings with the help of gonioscopy.
Seema Dutt Bandhu +3 more
doaj +1 more source
Recent advances in risk factors associated with ocular exfoliation syndrome
Acta ophthalmologica, 2019 Exfoliation syndrome is generally considered a progressive age‐related systemic disorder of the extracellular matrix, which is clinically characterized through the observation of flaky white aggregates on ocular tissues.
Mehdi Ghaffari Sharaf +2 more
semanticscholar +1 more source