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Genetics of Exfoliation Syndrome
Journal of Glaucoma, 2018Exfoliation syndrome (XFS) is an age-related systemic disorder of the extracellular matrix with important ocular manifestations. In this disorder, exfoliation material (XFM) is deposited in the anterior chamber of the eye on the lens, iris, ciliary body, as well as other intraocular structures.
Tin, Aung +2 more
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PURPOSE. To study the frequency of exfoliation syndrome (XFS) and its association with intraocular pressure (IOP) and systemic diseases in patients with age-related cataract scheduled for ...
M Irkec, Mehmet Orhan
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Histopathology of Exfoliation Syndrome
Journal of Glaucoma, 2018Exfoliation syndrome (XFS) is characterized by light and electron microscopy by age-dependent gradual accumulation of whitish material of largely unknown composition and origin along both the anterior and posterior chambers and widely within the iris stroma.
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Exfoliation Syndrome and Cataract Extraction
American Journal of Ophthalmology, 1993In a prospective study of 351 consecutive cataract operations performed on Finnish patients, the prevalence of exfoliation syndrome was 31% (108 of 351 eyes), increasing from 0% (zero of 54 eyes) in patients younger than 60 years to 15% (12 of 78 eyes) in patients aged 60 to 69 years, 42% (57 of 137 eyes) in patients aged 70 to 79 years, and 48% (39 of
P, Lumme, L, Laatikainen
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Aqueous Dynamics in Exfoliation Syndrome
American Journal of Ophthalmology, 1992Eighteen untreated patients with unilateral exfoliation syndrome without glaucoma were studied with regard to differences in aqueous dynamics between the affected and unaffected fellow eyes. Additionally, both eyes of the patients with exfoliation were compared to the eyes of 18 age-matched and gender-matched control subjects.
N Z, Gharagozloo +2 more
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Exfoliation Syndrome: A Historical Perspective
Journal of Glaucoma, 2018The discoverer of exfoliation was John Lindberg of Helsinki, Finland. He conducted his research as a young ophthalmology resident with the aim of elucidating 2 types of age-related degenerations of the iris and presenting it as an academic thesis. To this end, he had to construct a slit lamp, because they were not commercially available.
Tarkkanen A., Tarkkanen A.
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The Basement Membrane Exfoliation Syndrome
Archives of Ophthalmology, 1979Previous observations suggest that "pseudoexfoliation of the lens capsule" may be a disease in which cells produce abnormal basement membrane material. Electron microscopic studies indicate that exfoliative material can be produced by cells throughout the anterior segment of the eye.
R C, Eagle, R L, Font, B S, Fine
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Exfoliation Syndrome and Cataract Surgery
Journal of Glaucoma, 2018Cataract extraction in exfoliation syndrome requires careful preoperative assessment and planning. Knowledge of the degree of pupil dilation and zonular integrity are essential for safely perform cataract surgery in these eyes. Capsule rhexis should be 5.5 mm and all intraoperative maneuvers should be designed to minimize zonular stress.
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Vascular Dysfunction in Exfoliation Syndrome
Journal of Glaucoma, 2018Both exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) are associated with systemic vascular diseases and abnormalities. Although no uniform relationship between XFS/XFG and clinical systemic vascular diseases has been established across various populations, vascular dysfunction with or without clinically significant consequences has been ...
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Mechanisms of Glaucoma in Exfoliation Syndrome
Journal of Glaucoma, 2018The most important characteristic of exfoliation syndrome (XFS) is that it involves a greater risk of developing glaucoma. In comparison with other forms of open-angle glaucoma, exfoliation glaucoma is more resistant to medical therapy and progresses faster.
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