Results 61 to 70 of about 11,316 (195)

Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma

, 2008
Purpose: To evaluate genetic susceptibility of lysyl oxidase-like 1 (LOXL1) gene polymorphisms to exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) in a case-control cohort of American and European patients.
Spiteri, Anthony, Tarkkanen, A, Sarfarazi, M, O\u27Brien, Colm, Ritch, Robert, Tarkkanen, Ahti, Child, AH, Aragon-Martin, JA, Spiteri, A, Liebmann, Jeffrey, Liebmann, J, Cobb, CJ, Blaaow, Karima, Mercieca, Franco, Mercieca, F, Damji, KF, O'Brien, C, Blaaow, K, Rezaie, T, Cobb, Caroline J, Damji, Karim F, Ritch, R, Aragon-Martin, Jose A   +22 more
core   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Increased concentration of tumour necrosis factor alpha in the plasma of glaucoma patients [PDF]

Vojnosanitetski Pregled
Background/Aim. Changes in the concentration of various mediators of inflammation in blood, aqueous humor, or eye tissues support the role of inflammation in the pathogenesis of open-angle glaucoma (OAG).
Trenkić Marija, Jevtović-Stoimenov Tatjana, Bašić Jelena, Vasilijević Jelena, Ristić Dragana, Trenkić Milan, Veselinović Aleksandar, Cvetanović Marija   +7 more
doaj   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Association of Cogan-Reese Syndrome, Exfoliation Syndrome, and Secondary Open-Angle Glaucoma

, 2011
Purpose To present a case with co-existence of Cogan-Reese syndrome and exfoliation syndrome. Case report A 72-year-old Caucasian woman presented for consultation due to uncontrolled intraocular pressure (IOP) of the right eye.
Anastasios G.P. Konstas, Gábor Holló, Péter Kóthy   +2 more
core   +1 more source

Transient expression of Wnt5a elicits ocular features of pseudoexfoliation syndrome in mice.

PLoS ONE, 2019
PURPOSE:Pseudoexfoliation (PEX) syndrome is an age-related systemic disease with ocular manifestations. The development of animal models is critical in order to elucidate the cause of the disease and to test potential treatment regimens.
Yong Yuan, Ursula Schlötzer-Schrehardt, Robert Ritch, Mindy Call, Fred B Chu, Fei Dong, Taylor Rice, Jianhua Zhang, Winston W-Y Kao   +8 more
doaj   +1 more source

Unilateral ductus deferens aplasia with terminal cystic dilation in a Bernese mountain dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract An incidental caudal abdominal mass was discovered in a 5‐year‐old, male, entire Bernese mountain dog. Investigations showed a terminal cystic dilation of the left ductus deferens. Castration, along with surgical resection of the mass, was performed, and histopathology of the mass and ductus deferens was consistent with segmental aplasia of ...
Daisy Johnson, Louisa Price, Marie Beales, Joanna Stephenson   +3 more
wiley   +1 more source

Cutaneous Adverse Drug Reactions Associated With BRAF and MEK Inhibitors: A Real‐World Analysis of WHO Pharmacovigilance Data

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 274-285, July 2026.
BRAF inhibitors and MEK inhibitors (MEKi) have reshaped the treatment of BRAFV600‐mutant malignancies; however, cutaneous adverse drug reactions (ADRs) remain a frequent and clinically impactful toxicity. Although clinical trials provide insight into their safety profiles, real‐world data on dermatologic ADRs are limited.
Natalia Sauer, Piotr Giedziun, Jacek Calik, Anna Wiela‐Hojeńska   +3 more
wiley   +1 more source

Correlations between amyloid-β peptide levels in aqueous humor and retinal thickness in patients with glaucoma

Scientific Reports
Amyloid-β (Aβ) accumulation is a well-established cause of neurotoxicity in the brain and a major factor in Alzheimer’s disease. However, its role in ocular neurodegeneration remains unclear.
Tsutomu Ohashi, Takayuki Harada, Kazuhiko Namekata, Yasuhiro Shinmei, Akio Fujiya, Maiko Yoshida, Takashi Kojima   +6 more
doaj   +1 more source