Results 141 to 150 of about 52,967 (287)

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Respiratory and Cardiac Phase Coupling With Voluntary Actions Across Motor Tasks. [PDF]

Psychophysiology
Shibata H, Ohira H.
europepmc   +1 more source

Challenges faced by adolescents and lung function technicians in Anuradhapura district, Sri Lanka, during spirometry: a qualitative study. [PDF]

Int Health
Perera D, Nayakarathne G, Chandrasiri P, Ananda K, Nuwangi H, Rajapakse S.   +5 more
europepmc   +1 more source

Response to the Letter to the Editor by Zambelli et al for In Silico Lung Deposition Profiles of Three Single-Inhaler Triple Therapies in Patients With COPD Using Functional Respiratory Imaging [Response To Letter]. [PDF]

Int J Chron Obstruct Pulmon Dis
Singh D, Roche N, Wu L, Sadafi H, De Backer J, Monshi Tousi N, Marshall J.   +6 more
europepmc   +1 more source

Childhood Fractional Exhaled Nitric Oxide Predicts Incident Allergic Rhinitis in Adolescence and Young Adulthood

Allergy, EarlyView.
Chin‐Hung Wang, Jing‐Long Huang, Hui‐Ju Tsai, Hsin‐Yi Huang, Yu‐Lun Tseng, Tsung‐Chieh Yao   +5 more
wiley   +1 more source

Using electrical impedance tomography to estimate tidal volume in bottlenose dolphins and cape fur seals in seawater and on land. [PDF]

J Exp Biol
Fahlman A, Wells RS, West N, Allen A, Jabois A, Gallagher T, Larsson J, Strom E, Mosing M, Harake T, Adler A.   +10 more
europepmc   +1 more source

Prevalence of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease Patients With Frequent Exacerbations

Allergy, EarlyView.
Mireille C. Melles, Johannes C. C. M. in 't Veen, Dirk‐Jan Slebos, Frits M. E. Franssen, Marlies van Dijk, Pieter‐Paul W. Hekking   +5 more
wiley   +1 more source

Breathin' on the edge - the hidden complexity of pilot breathing regulators. [PDF]

Front Physiol
Messo K, Mansikka H.
europepmc   +1 more source

Influence of breathing strategies on maximal strength output and hemodynamic parameters during bench press exercise. [PDF]

BMC Sports Sci Med Rehabil
Deniz IE, Erdemir I.
europepmc   +1 more source

Disproportional ventilatory response to incremental exercise in individuals with cerebral palsy

Developmental Medicine &Child Neurology, EarlyView.
Individuals with cerebral palsy demonstrate a disproportionate ventilatory response during incremental exercise. Compared with typically developing peers, respiratory frequency increases earlier and at comparable exercise intensities, contributing to higher perceived exertion and reduced ventilatory efficiency. At task failure, respiratory frequency is
Linnéa Corell, Emma Hjalmarsson, Rodrigo Fernandez‐Gonzalo, Annika Kruse, Sebastian Edman, Asta Kizyte, Rouli Wang, Arnoud Edelman Bos, Peder Sörensson, Eva Pontén, Petra E. M. van Schie, Annemieke I. Buizer, Jessica Norrbom, Daniele A. Cardinale, Ferdinand von Walden   +14 more
wiley   +1 more source