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Exhaled nitric oxide in preterm infants
Respiration Physiology, 1998Nitric oxide (NO) is detectable in the exhaled gas of adults during spontaneous respiration and, according to current knowledge, mainly originates from the paranasal sinuses. We studied total NO excretion rates by chemiluminescence in preterm infants whose paranasal sinuses are known to be only partially pneumatized.
A, Artlich +5 more
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Exhaled nitric oxide in childhood asthma
European Journal of Pediatrics, 1996Endogenous synthesis of nitric oxide (NO) and its presence in exhaled air was observed in various species including humans. Particularly high levels were found in adults with bronchial asthma, possibly because of the underlying pulmonary inflammatory activity.
A, Artlich +4 more
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Exhaled nitric oxide in the assessment of asthma
Current Opinion in Pulmonary Medicine, 2004Asthma is now defined as a TH2-mediated inflammatory disease involving both large and small airways. However, assessment of airways inflammation is limited by techniques that are time consuming and possibly distressing to the patient. Exhaled nitric oxide, an easily and rapidly obtained noninvasive study, is a potential surrogate for measuring airways ...
Michelle R, Zeidler +2 more
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Exhaled nitric oxide comes of age
Journal of Breath Research, 2012The measurement of exhaled nitric oxide (NO) made its way as a new lung function from basic discovery to clinical application in less than a decade. As was the case with spirometry, after the initial bloom of the field, making and following basic discoveries, contradictory findings and unexpected discoveries brought the area to a halt, and scientists ...
Ildiko, Horvath +2 more
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Exhaled Nitric Oxide During Exercise
Sports Medicine, 1999Endogenously produced nitric oxide (NO) is detectable in the exhaled air of resting humans, and the amount of exhaled NO increases during exercise. It is believed that NO is likely to have an important role in the normal physiological response to exercise.
A W, Sheel, J, Road, D C, McKenzie
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Role of exhaled nitric oxide in asthma
Immunology & Cell Biology, 2001Nitric oxide (NO), an evanescent atmospheric gas, has recently been discovered to be an important biological mediator in animals and humans. Nitric oxide plays a key role within the lung in the modulation of a wide variety of functions including pulmonary vascular tone, nonadrenergic non‐cholinergic (NANC) transmission and modification of the ...
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Determinants of Exhaled Nitric Oxide in Chronic Rhinosinusitis
Chest, 2010Chronic rhinosinusitis (CRS) has been reported to be associated with increased values of exhaled nitric oxide (ENO), which could not be entirely explained by the association between CRS and asthma. The aim of this study was to investigate the variables associated with increased ENO in patients with CRS.This was a prospective cross-sectional descriptive
Giuseppe, Guida +11 more
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Exhaled nitric oxide in pediatric asthma
Current Allergy and Asthma Reports, 2008Exhaled nitric oxide can now be measured in a clinical setting as a noninvasive, reproducible, facile, point-of-service test to measure airway inflammation, a central component of asthma that had not been assessed previously. An excellent surrogate marker of steroid-responsive eosinophilic airway inflammation, it serves to identify steroid-sensitive ...
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Fraction of Nitric Oxide in Exhaled Breath
Clinics in Chest MedicineNitric oxide (NO) is an odorless gaseous molecule important for biological functions including regulation of vasodilation, smooth muscle relaxation, neurotransmission, platelet aggregation inhibition, and airway epithelial barrier function. It was first discovered in exhaled breath by Gustafsson and colleagues in 1991.
Amisha, Barochia, Loretta G, Que
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