Results 61 to 70 of about 9,097,159 (286)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An Experimental Study on the Efficacy of Local Exhaust Systems for the Mitigation of Exhaled Contaminants in a Meeting Room

Buildings
In industrial applications, local exhaust systems have been used extensively for capturing and confining contaminants at their source. The present study investigates the efficacy of these systems in mitigating the spread of exhaled pollutants by ...
Muhammad Farhan Ejaz, Simo Kilpeläinen, Panu Mustakallio, Weixin Zhao, Risto Kosonen   +4 more
doaj   +1 more source

A novel methodology and new concept of SARS-CoV-2 elimination in heating and ventilating air conditioning systems using waste heat recovery

AIP Advances, 2020
Heating and ventilation air conditioning systems in hospitals (cleanroom HVAC systems) are used to control the transmission/spreading of airborne diseases such as COVID-19.
Naser Rezaei, Moharram Jafari, Ata Nazari, Sina Salehi, Faramarz Talati, Reza Torab, Rahim Nejad-Rahim   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Analysis of the vehicle exhaust system corrosion and its effect on the ECO-test result

Metalurgija, 2022
This paper deals with analysis of the vehicle exhaust system quality and its influence on the results of measuring exhaust emissions of the Otto and Diesel motor vehicles. Results of eco-tests obtained from correct and faulty vehicle exhaust systems were
T. Šolić, D. Marić, S. Suhi, I. Samardžić   +3 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Experimental study on variable frequency control and air leakage control of multi-fan combination in subway tunnels

Scientific Reports
In centralized smoke exhaust emergency ventilation systems for metro tunnels, axial supply fans are often located far from the tunnel exit due to complex terrain constraints.
Guo Ying, Peng Wenqing, Chen Shiqiang, Wang Jiawei, Chen Ying   +4 more
doaj   +1 more source

Decarbonization Pathways in Underground Mining in Cold and Arctic Climates: A Review of Heat Recovery Systems with Case Studies in Canada

Energies
In cold climates, mine air conditioning systems are essential for preventing liners and shaft components from freezing. Traditionally, fossil fuel burners are used to heat intake air, resulting in high energy consumption and significant greenhouse gas ...
Hosein Kalantari, Seyed Ali Ghoreishi-Madiseh   +1 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source