Advanced Science, EarlyView.ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin +16 more
wiley +1 more source
The link between work-leisure conflict and cognitive pre-sleep arousal is serially mediated by emotional exhaustion and entrapment. [PDF]
Sci RepAydemir B, Ülbeği İD, Çetinkaya G.
europepmc +1 more source
Burnout Risk Among Providers of an Integrated Care Program Supporting Transitions Between the Hospital and Home: A Descriptive Mixed Methods Evaluation. [PDF]
Int J Environ Res Public HealthOrach J +14 more
europepmc +1 more source
Early sex-related transcriptional differences in CD8<sup>+</sup> T cells responding to chronic viral infection reveal a sex bias in exhaustion. [PDF]
Front ImmunolKahia N +9 more
europepmc +1 more source
Perceived stress and risky driving among emergency medical services personnel: parallel mediation effects of cognitive failures and emotional exhaustion. [PDF]
Front Public HealthAlasqah W, Noureldin A.
europepmc +1 more source
Redirecting Cholesterol Metabolism During <i>Ex Vivo</i> Biomanufacturing Enhances the Metabolic Fitness and Antitumor Efficacy of CAR-T Cells. [PDF]
Int J Biol SciZhu Y +11 more
europepmc +1 more source