Results 131 to 140 of about 828,499 (287)
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Within the turbomachinery industry, components are currently assessed deploying standard second-order steady solvers. These are unable to capture complicated unsteady phenomena that have a critical impact on component performance.
Guglielmo Vivarelli +8 more
doaj +1 more source
Dana Clancy: Intimate Distance [PDF]
This is the catalogue of the exhibition "Dana Clancy" at Boston University Art ...
Clancy, Dana
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Optimization of the ionoSolv process for the preservation of pulp fibre dimensions
The pulping industry, dominated by century-old technologies, is highly polluting, making imperative finding more environmentally friendly alternatives. The ionoSolv process, based on the use of low-cost protic ionic liquids, is one of the most promising ...
Shuyu Luan +5 more
doaj +1 more source
V pričujočem prispevku s pomočjo teoretskega pojmovanja spomina, kritične analize diskurza in multimodalne analize analiziramo narativne elemente razstave "Jugoslavija: od začetka do konca", ki je bila postavljena v beograjskem Muzeju jugoslovanske zgodovine, pri čemer identificiramo in analiziramo muzejske diskurze v postjugoslovanski tranzicijski ...
openaire +3 more sources
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Plains of Mars, European War Prints, 1500-1825
Over fifty original prints by renowned artists from the sixteenth through the early nineteenth century, including Albrecht Dürer, Lucas Cranach, Théodore Géricault, and Francisco de Goya, among many others, are featured inThe Plains of Mars: European War
Casale, Melissa +3 more
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