Results 21 to 30 of about 53,865 (267)
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Within China’s “Central China Rising” strategy, urban tourismification operates as a production mode that reconfigures spatial, economic, and ecological systems—mirroring global overtourism challenges seen in Barcelona and Venice, where rapid ...
Hexiang Zhang +3 more
doaj +1 more source
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
Myristoylation profiling in human cells and zebrafish
Human cells (HEK 293, HeLa, MCF-7) and zebrafish embryos were metabolically tagged with an alkynyl myristic acid probe, lysed with an SDS buffer and tagged proteomes ligated to multifunctional capture reagents via copper-catalyzed alkyne azide ...
Malgorzata Broncel +6 more
doaj +1 more source
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +5 more sources
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
GLAT: The generative AI literacy assessment test
The rapid integration of generative artificial intelligence (GenAI) technology into education requires precise measurement of GenAI literacy to ensure that learners and educators possess the skills to engage with and critically evaluate this ...
Yueqiao Jin +3 more
doaj +1 more source
This review examines metal enhanced fluorescence (MEF) using gold (Au) nanostructures, with a focus on biomedical applications of this phenomenon, namely fluorescence biosensing and imaging.
C. Joyce, S.M. Fothergill, F. Xie
doaj +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source

