Results 81 to 90 of about 203,939 (301)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
L’invention de la préhistoire par les objets
Les Nouvelles de l’Archéologie, 2012 The archaeological collections which Jacques Boucher de Perthes 1788-1868) sent in 1860 to the National natural history museum, remain little known.
Rachel Orliac
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Animating the Archive: The trial and testimony of a Sufi saint [PDF]
, 2016 In 1895 the colonial administration of Senegal sentenced Sheikh Amadu Bamba to exile for stirring anti-colonial disobedience. At his trial, Bamba allegedly recited a prayer in defiance of the French authorities.
De Jong, Ferdinand
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Perspetivas sobre a representação das monções no Museu Paulista e no Museu Republicano de Itu
Midas: Museus e Estudos Interdisciplinares, 2019 The article examines the appropriation of nineteenth-century scientific illustrator’s works – produced during the Langsdorff expedition (1825-1829) – by Afonso d’Escragnolle Taunay (1876-1958) during his time as director of the Museu Paulista in São ...
Maria Aparecida de Menezes Borrego
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New life to Italian university anatomical collections: desire to give value and open museological issues. Cases compared [PDF]
, 2019 The anatomical museums are one of the most difficult categories of museums to deal with because the issues addressed and the stored materials are complex to communicate and often not suitable for all audiences. The history of medicine teaches us that the
Ballestriero, Roberta +3 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Altre Modernità, 2011 My essay argues with the Exhibition of Italian Art 1200-1900 at the Burlington fine Arts Club, made possible by Mussolini and Lady Ivy Chamberlain in 1930. It focuses on the development and deployment of the aesthetic display resources theorized by Roger
Barbara Clara Borghi
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Boston Hospitality Review: Spring 2013 [PDF]
, 2013 Lodging Update: Providence, Rhode Island by Rachel Roginsky and Matthew Arrants -- Brand Heritage and Heritage Tourism by Bradford Hudson -- Te Front Desks of Boston by Michael Oshins -- Defining the New Luxury: Perspectives from Industry Leaders by ...
Arrants, Matthew +6 more
core +1 more source