Results 101 to 110 of about 34,330 (304)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

A Grammar of Space [PDF]

open access: yes, 2011
'A Grammar of Space' takes some of the questions on the relationship between a territory and its descriptions, developed in Spatial Narratives (National Gallery Prague June 2011) and discusses those in a different materiality and aesthetic logic.
Wallen, LP
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

MINUS SPACE en Oaxaca [PDF]

open access: yes, 2012
Instituto de Artes Graficas is a Mexican museum in Oaxaca. This was a group exhibition dealing with international ideas and research outcomes within conceptual and abstract art that was organised by the gallery in New York I am represented by Minus Space.
Jenkins, Kyle
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

At the jetty: rumination on time and space [PDF]

open access: yes, 2015
Invited curator for the Moose on the Loose 2015 Biennale (PARC/LCC/UoA) Karen Shepherdson with Rob Ball have curated a two-day exhibition and event at the Old Lookout Gallery on the Jetty on Broadstairs.
Ball, R., Shepherdson, K.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Organisation [PDF]

open access: yes, 2017
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Royal Exhibition Building Trustees
core  

A Tale of Two Cities and One Exhibition

open access: yesMiranda: Revue Pluridisciplinaire du Monde Anglophone
This study focuses on the interpretation labels of two city museums, the Cité des Sciences, and the Museum of London, and more specifically on those used in the exhibition “La Ville est à Nous”/ “The City is Ours” which was held in both cities.
Linda Pillière
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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