Results 81 to 90 of about 34,555 (299)
Entre soin et réemploi : vers une idée de scénographie durable avec Home Sweet Home
In the face of the climate emergency and the need for an ecological transition, the transformation of the cultural sectors requires a deep overhaul of operating modes and professional practices, especially in the field of exhibition design. This piece of
Chiara Rubessi
doaj +1 more source
Imaginer les visiteuses : Scripts de genre et conception d’une exposition
Recent studies has shown gendered stereotypes and representations at work in exhibitions about scientific culture, in their scenography or their médias.
Marion Coville
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
"Arates" by Steve Bickley. Collegiate Legacy: Emeritus Faculty Exhibition [PDF]
Exhibition of works by College of Architecture and Urban Studies emeritus faculty, celebrating the 50th anniversary of the college. Curated by Truman Capone and Deb Sim. Moss Arts Center, Virginia Tech.STEVE BICKLEY. Arates. 1966. Painted steel. Courtesy
Bickley, Steve
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
"Angel Urn" by Ellen Braaten. Collegiate Legacy: Emeritus Faculty Exhibition [PDF]
Exhibition of works by College of Architecture and Urban Studies emeritus faculty, celebrating the 50th anniversary of the college. Curated by Truman Capone and Deb Sim. Moss Arts Center, Virginia Tech.ELLEN BRAATEN. Angel Urn. 1966. Clay.
Braaten, Ellen B.
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

