Results 121 to 130 of about 341,227 (353)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

“Towards the revival of religious art”.[1] The revival efforts for church art in Polish Lands between 1900–1939 (with particular emphasis on wall-paintings)

open access: yesSacrum et Decorum, 2013
For over 200 years now, that is, at least since the French Revolution, religious, or church art has been plagued with the notion of its inadequacy to the expectations of the faithful and the resulting need for the “eternal resurrections of sacred art ...
Joanna Wolańska
doaj  

Exhibiting Yugoslavia [PDF]

open access: yesDružboslovne Razprave, 2015
V pričujočem prispevku s pomočjo teoretskega pojmovanja spomina, kritične analize diskurza in multimodalne analize analiziramo narativne elemente razstave "Jugoslavija: od začetka do konca", ki je bila postavljena v beograjskem Muzeju jugoslovanske zgodovine, pri čemer identificiramo in analiziramo muzejske diskurze v postjugoslovanski tranzicijski ...
openaire   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

“The Great Migration Period” – a new exhibition in the State Hermitage Museum

open access: yesTyragetia, 2018
At December 1, 2017, a permanent exposition of the State Hermitage (St. Petersburg) was opened after the reconstruction, under the title “Europe in the Great Migration Period and Early Middle Ages”.
Alexei Furasiev
doaj  

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