Results 121 to 130 of about 435,580 (348)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
For scientists, for students or for the public? : the shifting roles of natural history museums [PDF]
, 2010 This article aims to discuss the main roles of natural history museums and to show how these purposes have evolved and adapted throughout the museums’ history, as a response to the development of natural sciences and societal change, from their creation ...
Delicado, Ana
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Diacronie. Studi di Storia Contemporanea, 2014 Russia took part almost in all World Exhibitions of the second half of the 19th century. Starting with sections in the central exhibition hall, it gradually expanded its presence at exhibitions at the expense of separate thematic buildings and big ...
Olga Kazakova est Docteur en Histoire. Son intérêt principal est l’imagologie des relations internationales. Surtout spécialiste du XIX siècle elle étudie les différentes institutions et formes de la présentation et de la perception de l’image de l’Autre. Actuellement elle s’occupe de l’image de la Russie à travers des Expositions Universelles.
doaj
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source