Results 161 to 170 of about 11,966 (266)
The spirit of Ewha, carried forward through devotion: an interview with Dr. Kumie Oh, alumna of the 27th graduating class, anesthesiologist. [PDF]
Kwon N, Kim J.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Utilizing unstructured data to predict the art museum visitor numbers using deep learning approaches. [PDF]
Tian Z, Wang X, Tan Y, Na HJ, Kim C.
europepmc +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
EEG data of museum visitors experiencing visual and audiovisual simulations of Edzná, an archaeological site in Mexico. [PDF]
Luz María AV +6 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Association Between Wearable Device Adoption and Health-Related Lifestyle Behaviors: Retrospective Cohort Study. [PDF]
Choi E, Choi S, Jang SY.
europepmc +1 more source

