Results 51 to 60 of about 11,966 (266)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Exhibitions in a Political Context and Their Impact on Knowledge Democracy
Parliaments play a key role in the concept of knowledge democracy. They contribute to the production and dissemination of knowledge, promote critical thinking and opinion formation, and strengthen democracy through high-quality laws.
Matthias Keppel
doaj +1 more source
L’archéologie de l’or en Europe
In such a long-standing discipline as archeology, research on gold metallurgy used to hold a secondary position, until things began to change in the 1990s.
Alicia Perea, Barbara Armbruster
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Relegated to the margins of the history of 19th century German art, the Nazareans and the painters of the Düsseldorf school have long been disparaged, their art considered sterile and backward-looking by some, and academic and bourgeois by others.
France Nerlich
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
‘A material influence imperceptibly exercised on the taste and judgement of the public’: The Burlington Fine Arts Club and the history of collecting [PDF]
Founded in 1866 by the South Kensington curator John Charles Robinson, the Burlington Fine Arts Club played a critical role in the landscape of collecting and display over its near century long history.
Eloise Donnelly
doaj
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

