Results 71 to 80 of about 3,141 (306)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Les échanges artistiques entre la France et les États-Unis, 1950-1968
Perspective, 2011 In the last two and a half decades, there has been a dramatic increase in scholarship about artistic exchanges between France and the United States during the first two decades of the Cold War.
Sarah K. Rich
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Architectural exhibitions from forties to sixties of 20th century in Prague. [PDF]
The main topic of diploma theses are Prague exhibitions, which were presenting contemporary or historical architecture from year 1940 to 1970. Goal of this research is to systematically investigate Czech architectural projects from the point of view of ...
Dědičová, Magdalena
core +1 more source
Hot topic: Influenza A H5N1 virus exhibits a broad host range, including dairy cows
JDS CommunicationsThe widespread circulation of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b in wild birds in North America since late 2021 has resulted in multiple outbreaks in commercial and backyard poultry leading to major economic losses. Since the emergence of the virus in North America, multiple reassortment events have led to the emergence of ...
Salman L. Butt +3 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Práticas da História, 2019 In 1960, Portugal celebrated the five-hundredth anniversary of the death of Prince Henry, a heroic figure acclaimed for his role in the early maritime dis- coveries. The celebrations lasted several months and were sponsored by the Portuguese state.
Benjamin R. J. Jennings +1 more
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Quarrying: an anthropogenic geomorphological approach [PDF]
Acta Montanistica Slovaca, 2008 The study intends to give an introduction to the significance of quarrying from the point of view of anthropogenic geomorphology, indicating the level of surface forming due to the mining of mineral raw materials.
Dávid Lóránt
doaj
Ideas of Slovakness: The formation of national identity discourse in the visual arts of the 1930s [PDF]
Slovenska LiteraturaAfter 1918, in the changed socio-political landscape following the establishment of Czechoslovakia, the search for national identity emerged as a key topic in intellectual discussions.
Lucia Kvočáková
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Sisyphus, 2014 Sisyphus - Journal of Education, Vol 2, Issue 2 (2014): Science Education in the 21st Century: Challenges and ...
Blonder, Ron, Meshulam, Inga
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