Results 261 to 270 of about 8,396,811 (368)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Do syngameons exist in tropical trees? Challenges to determine their existence and estimate their frequency. [PDF]

Biol Lett
Cervantes S, Schley R, Hardy OJ, Ojeda D.   +3 more
europepmc   +1 more source

Existence results for a quasi-linear differential problem

, 2011
Pasquale Pizzimenti, Angela Sciammetta
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Microchimerism and the need to rethink sex and gender binaries. [PDF]

Biol Sex Differ
Shildrick M.
europepmc   +1 more source

The Nature Perspective Providing Good Environment for Co-Existence of Species Extending to Disaster Management: A result of the Analysis of the New Consciousness model which scientifically converges Science and Spirituality with converged scientific and spiritual insights into the aspects of God, Soul, Karma, Birth and Re-birth, Machine Consciousness and Awareness, Plants, Animals, All Life, Natural and non-Natural forms and Convergence of Religious Teachings

, 2012
Neela Iyer, Prabhu Britto Albert, Sant Maa Ananta Devi, Sant Maa Aparna Devi, M. Mohanan, Dhyanyogi Omdasji Maharaj   +5 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

On the solution for a nonlinear wave equation with variable exponent nonlinearity and a varying delay. [PDF]

Sci Rep
Benguessoum A, Bensaid M, Boulaaras S, Souid MS.   +3 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

An Ethical Reflection on Assisted Dying, Inequity Within Palliative Medicine Services and Access to Care in the United Kingdom: A Resident Doctor's Perspective. [PDF]

Cureus
Hayden MW.
europepmc   +1 more source