Heavy‐element damage seeding in proteins under XFEL illumination
Plasma simulations with detailed modeling of unbound electron dynamics predict that heavy elements contribute significantly to radiation damage suffered by proteins in serial femtosecond crystallography. New methods to mitigate radiation damage in this regime are highlighted.Serial femtosecond X‐ray crystallography (SFX) captures the structure and ...
Spencer K. Passmore+3 more
wiley +1 more source
Modeling bacterial growth and Allee effect via Allen-Cahn theoretical framework. [PDF]
Maslovskaya A+4 more
europepmc +1 more source
Generalized neural closure models with interpretability. [PDF]
Gupta A, Lermusiaux PFJ.
europepmc +1 more source
A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains
Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley +1 more source
A Sparse Hierarchical <i>hp</i>-Finite Element Method on Disks and Annuli. [PDF]
Papadopoulos IPA, Olver S.
europepmc +1 more source
Modal better: A corpus‐based investigation in world Englishes
Abstract While previous studies have investigated the productivity of the better construction (in the forms had better, ’d better and better) in British and US English (USE), to present knowledge, no large‐scale comparisons on the use of this construction in other English dialects have been carried out.
Carmelo Alessandro Basile
wiley +1 more source
Stability of Breathers for a Periodic Klein-Gordon Equation. [PDF]
Chirilus-Bruckner M+2 more
europepmc +1 more source
Random walk on sphere packings and Delaunay triangulations in arbitrary dimension
Abstract We prove that random walks on a family of tilings of d$d$‐dimensional Euclidean space, with a canonical choice of conductances, converge to Brownian motion modulo time parameterization. This class of tilings includes Delaunay triangulations (the dual of Voronoi tessellations) and sphere packings.
Ahmed Bou‐Rabee, Ewain Gwynne
wiley +1 more source
Reducing phenotype-structured partial differential equations models of cancer evolution to systems of ordinary differential equations: a generalised moment dynamics approach. [PDF]
Villa C+5 more
europepmc +1 more source
Attention‐Based Reconstruction of Full‐Field Tsunami Waves From Sparse Tsunameter Networks
Abstract We investigate the potential of an attention‐based neural network architecture, the Senseiver, for sparse sensing in tsunami forecasting. Specifically, we focus on the Tsunami Data Assimilation Method, which generates forecasts from tsunameter networks.
Edward McDugald+4 more
wiley +1 more source