Results 51 to 60 of about 975 (193)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Stability Evaluation and Parametric Optimization of Coal‐Concrete Composite Bearing Systems Under Mine‐Water‐Induced Deterioration: Experiments and FEINN Analysis

Energy Science &Engineering, EarlyView.
Mine‐water immersion tests reveal pronounced coal weakening (vs. minor concrete degradation), identifying coal pillars as the stability‐limiting component in composite dams. A coupled FEINN framework quantifies extreme‐pressure stability and ranks multi‐parameter designs via a normalized multi‐indicator scheme, enabling optimized dam configuration for ...
He Wen, Hongchuan Dai, Guixin Zhang, Pengzhe Li, Tong Yang, Cang Gong, Renbo Gao   +6 more
wiley   +1 more source

Linear and Nonlinear Perturbed Wave Equations [PDF]

, 2008
We consider several Cauchy problems for the wave equation with some perturbation. First of all, we consider the wave equation with a metric perturbation, that is, we consider the d'Alembert operator in the Schwarzschild metric (which is a model for a ...
CATANIA, DAVIDE
core  

Associations Between DAT, CBSE, and USMLE Step 1 Exams Among Oral and Maxillofacial Surgery Residents

Journal of Dental Education, EarlyView.
ABSTRACT Purpose/Objectives The Dental Admission Test (DAT), Comprehensive Basic Science Examination (CBSE), and United States Medical Licensing Examination (USMLE) Step 1 are used to assess readiness in dental and medical education. This study examined associations between DAT scores (composite and subsections), CBSE scores, and USMLE Step 1 ...
Obadiah J. Pirlo, Felix J. Amarista, Daniel E. Perez   +2 more
wiley   +1 more source

Multidimensional asymptotic spectral analysis and applications [PDF]

This article adresses questions on localization and microlocalization in the framework of the so called (C,E,P)–algebras of generalized functions. We give new results on nonlinear properties of the asymptotic singular spectrum in the multi-parameter case,
Jean-André Marti, Richard Maximilian Hasler, Victor Dévoué   +2 more
core  

Foundations of continuous-time recursive utility : differentiability and normalization of certainty equivalents [PDF]

, 2009
This paper relates recursive utility in continuous time to its discrete-time origins and provides a rigorous and intuitive alternative to a heuristic approach presented in [Duffie, Epstein 1992], who formally define recursive utility in continuous time ...
Seifried, Frank Thomas, Kraft, Holger
core  

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak, Ahmed Javed, Ummi Aiman Rahman, Rumaisa Riaz, Zeeshan Imtiaz, Hassan A. Mirza, Farman U. Khan, Muhid Khattak, Fatima Javid, Abdul Moiz Khan, Adeline L. Roy, Bibek Shrestha   +11 more
wiley   +1 more source

GENERALIZED CRYSTALLINE EVOLUTIONS AS LIMITS OF FLOWS WITH SMOOTH ANISOTROPIES [PDF]

, 2018
International audienceWe prove existence and uniqueness of weak solutions to anisotropic and crystalline mean curvature flows, obtained as limit of the viscosity solutions to flows with smooth ...
Ponsiglione, Marcello, Massimiliano Morini, Antonin Chambolle, Chambolle, Antonin, Morini, Massimiliano, Marcello Ponsiglione, Novaga, Matteo, Matteo Novaga   +7 more
core   +1 more source

Uniqueness for Neumann Problems for Nonlinear Elliptic Equations With Lower Order Terms

Mathematische Nachrichten, EarlyView.
ABSTRACT In this paper, we prove uniqueness results for weak solutions to a class of Neumann problems, whose prototype is λ(1+u2)(p−2)/2u−div((1+|∇u|2)(p−2)/2∇u)−div(c(x)(1+|u|2)(τ+1)/2)+b(x)(1+|∇u|2)(σ+1)/2=finΩ(1+|∇u|2)(p−2)/2∇u+c(x)(1+|u|2)(τ+1)/2)·n̲=0on∂Ω,$$\begin{equation*} {\begin{cases} {}\lambda {(1+ u^2)}^{(p-2)/2}u-{\operatorname{div}}({(1+|\
Maria Francesca Betta, Olivier Guibé, Anna Mercaldo, Maria Rosaria Posteraro   +3 more
wiley   +1 more source

Unveiling New Perspectives on the Hirota–Maccari System With Multiplicative White Noise

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this study, we delve into the stochastic Hirota–Maccari system, which is subjected to multiplicative noise according to the Itô sense. The stochastic Hirota–Maccari system is significant for its ability to accurately model how stochastic affects nonlinear wave propagation, providing valuable insights into complex systems like fluid dynamics
Mohamed E. M. Alngar, Khaled A. Gepreel, Reham M. A. Shohib, Yakup Yildirim   +3 more
wiley   +1 more source