Results 191 to 200 of about 251,066 (317)

Forward and inverse optimality problems of bone adaptation at the homogenised RVE level. [PDF]

Biomech Model Mechanobiol
Zysset PK.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Understanding the impacts of extreme weather on biological control through traveling wave analysis of a prey-predator model. [PDF]

Sci Rep
Aktar MS, Yue Y, Bani-Yaghoub M, Ou C, Ali MA.   +4 more
europepmc   +1 more source

Existence and blow up of solutions to certain classes of two-dimensional nonlinear Neumann problems

, 2005
Kai Medville, Michael Vogelius
openalex   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Entropy of a Quasi-de Sitter Spacetime and the Role of Specific Heat. [PDF]

Entropy (Basel)
Luongo O, Azizinia M, Boshkayev K.
europepmc   +1 more source

Existence of weak solutions [PDF]

, 2013
openaire   +1 more source

Existence and homogenization of trajectory statistical solutions for the 3D incompressible Hall-MHD equations

Hujun Yang, Xiaoling Han, Caidi Zhao
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

A fractional model based on caputo derivative for tuberculosis transmission using real data from Kenya. [PDF]

Sci Rep
Bhatia B, Bhatter S, Purohit SD, Baleanu D, Suthar DL.   +4 more
europepmc   +1 more source