Results 51 to 60 of about 14,210 (206)

Evolution hesitancy: challenges and a way forward for teachers and teacher educators

Evolution: Education and Outreach, 2023
Background It has long been acknowledged that evolution is a difficult topic for many students, partly because of the conceptual demands it makes, and partly because for some students an acceptance of evolution conflicts with their religious beliefs. The
Emma Newall, Michael J. Reiss
doaj   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

The Transition from Existential to a Pure Geometrical space and its Phenomenological Justifications [PDF]

حکمت و فلسفه, 2018
In this paper, we shall demonstrate that the Cartesian approach to the res extensio and taking it as the most fundamental, essential determination of Vorhandenheit, though Descartes’ ontology is not rich enough to explain the relationship between pure ...
Ehsan Karimi Torshizi, Hedieh Yaghubi Bojmaeh   +1 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Abortion restrictions as a form of cascading collective trauma

Critical Public Health
Reproductive coercion, sexual violence, and intimate partner violence are rooted in patriarchal norms, and represent serious physical and mental health threats.
Selina Hardt, Rachel Williamson, Gabriella Graceffo   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Typy starzenia się aktywnych edukacyjnie osób starszych w kontekście egzystencjalnym

Colloquium
Being very much engaged in educational activities, active older learners are a unique group. That is why it is interesting to study how these people age.
Artur Fabiś , Marcin Muszyński
doaj   +1 more source

The use of transitional space in psychotherapy with the existential concerns of borderline experience

Revista Científica Arbitrada de la Fundación MenteClara, 2020
This paper describes experiencing the state of transitional awareness that facilitates the ongoing psychotherapy process within borderline states of concern.
Rudolph Bauer
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source