Results 71 to 80 of about 18,685,718 (259)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Feeling existentially touched – A phenomenological notion of the well-being of elderly living in special housing accommodation from the perspective of care professionals

International Journal of Qualitative Studies on Health & Well-Being, 2013
This article presents a phenomenological analysis of interview material, in which 12 care professionals in elderly care reflect on the elderly's well-being within the frame of special housing accommodation.
Anette Lundin, Lars-Erik Berg, Ulla Hellström Muhli   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Spiritual well-being of nursing professionals with work-related musculoskeletal disorders: a cross-sectional study [PDF]

Revista Gaúcha de Enfermagem
Objective: To analyze the spiritual well-being of nursing professionals with work-related musculoskeletal disorders. Method: Cross-sectional observational study, carried out with nursing professionals from a public university hospital in Bahia, Brazil ...
Luciana de Carvalho Feitoza, Márcia Carneiro de Santana Vivas, Mary Gomes Silva, Cristina Salles, Cíntia Mesquita Correia, Kátia Nunes Sá, Gilmara Ribeiro Santos Rodrigues   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Individual differences in gratitude and their relationship with well-being [PDF]

Ten studies are presented which show how and why individual differences in gratitude are related to well-being, with six key conclusions. Grateful people view the help they receive in everyday life as more costly, valuable, and altruistically intended.
Wood, Alexander Mathew
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Impact of Spiritual Well-Being on Multidimensional Perfectionism in University Students: A Nationwide Survey

European Journal of Investigation in Health, Psychology and Education
Background: Perfectionism is a multidimensional personality trait encompassing both adaptive and maladaptive aspects that strongly influence students’ psychological health.
Alessio Lo Cascio, Elena Sandri, Anna De Benedictis, Anna Marchetti, Giorgia Petrucci, Silvia Dsoke, Gianluca Pucciarelli, Rosaria Alvaro, Maria Grazia De Marinis, Michela Piredda   +9 more
doaj   +1 more source

Aspects of well-being when struggling with obesity

International Journal of Qualitative Studies on Health & Well-Being, 2019
Purpose: We aimed to gain deeper insight into how people struggling with obesity handle their life situation by addressing how well-being might unfold.
Britt Marit Haga, Bodil Furnes, Elin Dysvik, Venke Ueland   +3 more
doaj   +1 more source