Results 131 to 140 of about 563,567 (216)

ReFraming The FaPMI (Families Where a Parent Has a Mental Illness) Program: Using a Participatory Action Research Approach to Create Change. [PDF]

Int J Ment Health Nurs
Allchin B, Morgan A, Clark C, Jewell H, Legge J, Schinas J, Mack H, McCall A, Cameron D, Chalmers A, Cosgriff C, Creswick A, Dickenson S, Forster I, Foster D, Fraser E, Harbor P, Hegarty M, Henley K, McCormack F, McGregor T, Nguyen AT, Rabbitt K, Sanders B, Sarikoudis V, Stead M, Stephenson N, Tesoriero L, Timmins G, Zinnack H.   +29 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Implementation Strategies for Strengthening Community and Stakeholder Engagement in Clinical and Translational Pilot Studies. [PDF]

J Particip Res Methods
Brewer SK, Chen S, Concannon TW, Sege RD, Rushforth A, Must A, Prokofieva N, Welch LC.   +7 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Integration of the patient, caregiver and community voice into paediatric care, education and research: the SickKids model of advisor-centred engagement. [PDF]

BMJ Open
Allemang B, Buchanan F, Medeiros P, Kinnear K, Czarny TL, Cohen E, Subbarao P, Haas K, Rose J, Jones M, Macarthur C.   +10 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Multiple paths to organisational capacity building in civilian rescue teams: evidence from a national survey in China. [PDF]

Disasters
Yang W, Lu Y.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Seismic performance assessment and strengthening of a residential RC building damaged in the 2023 Türkiye Earthquakes: A case study. [PDF]

Sci Rep
Peker FÜ, Yuzbasi J, Işık E, Avcil F, Büyüksaraç A.   +4 more
europepmc   +1 more source