Results 141 to 150 of about 528,775 (319)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

"Trying to Make Sense of the Bank of Japan's Monetary Policy since the Exit from Quantitative Easing" [PDF]

open access: yes
In this short note I review the Bank of Japan's monetary policy since its exit from the so-called quantitative easing regime early in 2006. The major characteristic of the policy stance during the period, called Strategy 2 below, has been to adjust the ...
Kazuo Ueda
core  

A quantitative framework for exploring exit strategies from the COVID-19 lockdown [PDF]

open access: yesChaos Solitons Fractals, 2020
Fokas AS   +2 more
europepmc   +2 more sources

An exit strategy for the tubercle bacillus? [PDF]

open access: bronze, 2008
Suzie Hingley‐Wilson, Ajit Lalvani
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

The financial crisis, trade finance and the collapse of world trade [PDF]

open access: yes
The financial crisis that began in August 2007 and intensified in the fall of 2008 pushed the global economy into its most severe recession since World War II.
Mark Wynne
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Exit strategies

open access: yesEnvironment and Planning A: Economy and Space
This paper approaches Quinn Slobodian’s work as a working guide to contemporary capitalist strategies of exit and containment. It asks what challenges this poses to anti-state critique from the left and what lessons might be learned.
openaire   +1 more source

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